Janaína Menezes Zanoveli;
Helen Morais;
Isabella Caroline da Silva Dias;
Anne Karoline Schreiber;
cAMILA pASQUINI SOUZA;
Cunha, Joice M.
Palavra-chave:
Depressão;
diabetes
Áreas do conhecimento:
Ciências Biológicas; Farmacologia; Neuropsicofarmacologia
resumo ...
Diabetes is a chronic and progressive syndrome commonly associated with several neuropsychiatric
comorbities, of which depression is the most studied. The ...
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Santiago, R.;
maria vital;
Marcelo D. O. sato;
Gustavo P. Adam
International Journal of Neurology and Neurotherapy,
v. 3,
n. 5,
p. 61-65,
2016
Palavra-chave:
depression;
Neuroinflamação;
Parkinson?s disease
Áreas do conhecimento:
Ciências Biológicas; Farmacologia; Neuropsicofarmacologia;
Ciências Biológicas; Farmacologia; Neuropsicofarmacologia; Doenças Neurodegenerativas
resumo ...
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Gabrielle Adad Fornazari;
Fabiano Montiani Ferreira;
Jeverson C. Silva;
Ivan Roque de Barros Filho;
Marcello Machado
Italian Journal of Anatomy and Embryology,
v. 121,
n. 2,
p. 21-30,
2016
Palavra-chave:
bat;
camel;
dromedary;
Evolution;
optic spine of the esphenoid bone
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia
resumo ...
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Gabrielle A Fornazari;
Fabiano Montiani Ferreira;
Jeverson C Silva;
Ivan Roque de Barros Filho;
Marcello Z. Machado
Palavra-chave:
morcego;
camelo;
dromedário
Áreas do conhecimento:
Ciências Biológicas; Morfologia; Anatomia; Anatomia Animal
resumo ...
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Salise Brandt Martins;
MAROCHI, MURILO ZANETTI;
Setuko masunari
Papéis Avulsos de Zoologia (São Paulo),
v. 56,
n. 14,
p. 163-169,
2016
Palavra-chave:
morfologia;
larvas de caranguejos
Áreas do conhecimento:
Ciências Biológicas; Zoologia; Morfologia dos Grupos Recentes
resumo ...
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Fabricio Martins Dutra;
Pedro Gusmão Borges Neto;
Sandra Carla Forneck;
Eduardo Luis Cupertino Ballester
Revista Brasileira de Engenharia de Pesca / Brazilian Journal of Fishing Engineering,
v. 9,
n. 1,
p. 27-36,
2016
Palavra-chave:
Carcinicultura;
Densidade;
recirculação
Áreas do conhecimento:
CIENCIAS_AGRARIAS; Aqüicultura;
Ciências Biológicas; Biologia Geral; Aquacultura; Carcinicultura
resumo ...
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André Luiz Gollo;
Carlos Ricardo Soccol;
André Luís Lopes da Silva;
K.K.D. Lima;
Jefferson da Luz Costa;
M.C. Camara;
Luis Antonio Biasi;
C. Rodrigues;
Luciana P. S. Vandenberghe;
Vanete Thomaz Soccol
Pakistan Journal of Botany,
v. 48,
n. 1,
p. 295-303,
2016
Palavra-chave:
Micropropagação;
Cultura de Tecidos;
meio de cultura
Áreas do conhecimento:
Ciências Biológicas; Biotecnologia Vegetal
resumo ...
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Audia Brito Rodrigues de Almeida;
Eric de Camargo Smidt;
Erika Amano
Palavra-chave:
Absorption;
fixation;
Ontogenesis;
Spiral-shaped trichomes;
Velamen
Áreas do conhecimento:
Ciências Biológicas; Botânica; Morfologia Vegetal; Anatomia Vegetal
resumo ...
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Amanda Gailit Balliana;
Barbara Baesso Moura;
Renata Charvet Inckot;
Cleusa Bona
Palavra-chave:
anatomia;
poluição por hidrocarbonetos;
Canavalia ensiformis
Áreas do conhecimento:
Ciências Biológicas; Botânica; Morfologia Vegetal; Anatomia Vegetal
resumo ...
Hydrocarbons are the main components of diesel oil and are toxic for the majority of plants. A few plant species, known as phytoremediators, are tolerant of hydrocarbons and can survive the stressful conditions of soils contaminated with diesel oil. Canavalia ensiformis, a plant species that is well distributed throughout the tropics, possesses advantageous features for a potential resistance to soil contamination, such as fast growth and a deep root system. Thus, the aim of the present study was to evaluate the tolerance of C. ensiformis when it was exposed to soil contaminated with diesel oil. Seedlings were subjected to two treatments: contaminated soil (CS) (95 ml/kg of diesel oil) and non-contaminated soil (NCS) for a period of 30 days; its growth, morphology, anatomy, and physiology were analyzed. Despite the high level of toxicity, some individuals were able to survive in CS. These plants had root apical meristems with high levels of mitosis and were able to issue new roots with more developed aerenchyma tissue. Because the surviving plants presented no marks of cellular damage on the organs formed (root and leaves) during the experiment, the species capacity of growth on CS was confirmed. Although, long-term field experiments, applying different contaminant concentrations, should be considered to infer about the species resistance and use as phytoremediator.
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CAMARGO, CAROLINA MACIEL;
Augusto, Danillo G.;
Maria Luiza Petzl-Erler
Palavra-chave:
LAIR1;
LAIR2;
Autoimmunity;
genetic susceptibility;
pemphigus foliaceus
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Imunologia; Imunogenética
resumo ...
The leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1) is a collagen-binding inhibitory receptor important for the regulation of immune responses, expressed on the majority of peripheral blood mononuclear cells (PBMC). LAIR-2 is a soluble homolog that antagonizes LAIR-1 inhibitory function by binding the same ligands. We sought to investigate whether LAIR1 and LAIR2 single nucleotide polymorphisms (SNP) are associated with differential mRNA expression levels. We analyzed 14 SNPs of LAIR1 (6) and LAIR2 (8) by mass spectrometry-based genotyping and extracted mRNA from PBMC of 177 healthy subjects, followed by quantitative assays. Four SNPs of LAIR1 and two SNPs of LAIR2 mark differential mRNA levels in healthy individuals. To verify the biological relevance of these findings, we analyzed additional 515 individuals (282 patients and 233 controls) to check if LAIR1 and LAIR2 differential mRNA expression could be related to susceptibility to pemphigus foliaceus (PF), an autoimmune blistering skin disease endemic in Brazil. Two LAIR1 variants (rs56802430
G, OR = 1.52, p = 0.0329; rs11084332 C, OR = 0.57, p = 0.0022) and one LAIR2 (rs2287828
T+, OR = 1.9, p = 0.0097) contribute to differential susceptibility to PF. Furthermore, we demonstrate interactions among four LAIR2 SNPs (rs2042287, rs2287828, rs2277974 and rs114834145). A haplotype harboring these SNPs is strongly associated with higher LAIR2 mRNA levels (4.5-fold, p = 0.0069) and with higher susceptibility to PF (OR = 4.02, p = 0.0008). We suggest that LAIR1 and LAIR2 genetic variants are associated with regulation of gene expression and variable PF susceptibility, and show indirect association of LAIR2 differential mRNA expression with PF pathogenesis. Our data demonstrate how this relatively unknown disease can add invaluable knowledge regarding the role of LAIR1 and LAIR2 in immune responses.
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