Publicações - ciências da saúde
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OLIVEIRA, RAFAELA MOURA DE;
SCHNEIDER, MARIA CAROLINA;
GOMES, IZABELLA RODRIGUES REIS;
GOIS, LARISSA HABIB MENDONÇA;
MORGAN, MARIANA APARECIDA PASA;
Kerstin Taniguchi Abagge
Palavra-chave:
Analytical chemistry techniques;
Skin;
skin care;
Child health;
soaps;
pH
resumo ...
ABSTRACT Objective: The aim of this study was to evaluate the surface hydrogen potential (pH)...
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Leticia D V Henschel;
Maria Eduarda Rizzardi Lima;
E H Luz;
ZAZULA, MATHEUS FELIPE;
Katya NALIWAIKO;
Luis Cláudio Fernandes
Palavra-chave:
cancer cachexia;
tumor;
clenbuterol;
Metformin;
walker 256
Áreas do conhecimento:
Ciências Biológicas; Fisiologia; Fisiologia de Órgãos e Sistemas; Fisiologia Endócrina;
Ciências da Saúde; Nutrição; Desnutrição e Desenvolvimento Fisiológico;
Ciências da Saúde; Medicina; Oncologia
resumo ...
Cancer is the second leading cause of death worldwide. Cancer cachexia is a multifactorial...
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Francisco de Assis Mendonça;
Felipe José Soek;
Antonio Carlos da Silva Oscar Junior;
Daniel Canavese;
Maurício Polidoro;
Thiago Kich Fogaça
Palavra-chave:
Dengue;
Emergencia climática;
Doenças emergentes;
Brazil;
Negleted Diseases
Áreas do conhecimento:
Ciências Exatas e da Terra; Geociências; Geografia Física; Climatologia Geográfica;
Ciências da Saúde; Saúde Coletiva; Epidemiologia
resumo ...
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Rasera, Ana Helena Willrich;
SPAUTZ, CLEVERTON CESAR;
Iris Rabinovich;
URBAN, CICERO;
ANSELMI, KARINA FURLAN;
Ana Clea Andrade;
Ana Paula Martins Sebastião
Palavra-chave:
Breast cancer;
Ki67;
Oncotype Dx®
Áreas do conhecimento:
Ciências da Saúde; Farmacologia; Transmissão Neuromuscular
resumo ...
Introduction: In early-stage breast cancer, there is a constant search to identify which patients will benefit from chemotherapy. Among the most widely used genetic tests is Oncotype DX®, a validated prognostic marker. However, its high cost is still a major limitation. As a more financially viable alternative, the cell proliferation index determined by the Ki67 antigen is used.Objective: To evaluate the percentage of Ki67 expression and its relationship with the Oncotype DX® recurrence score in luminal breast carcinomas.Methods: 79 Oncotype DX® results available in the last 5 years were analyzed and compared with the respective anatomopathological and immunohistochemical reports.Results: The mean age was 56 years with tumors ≤ 2 cm (72.2%), with a predominance of carcinomas of no special type (73.4%) and tumor grade 2 (72.2%). Among patients under 50 years of age, intermediate risk was the most common (60.7%). In this group, the cutoff point for Ki67 by ROC curve adjustment was 37% (p=0.032), with sensitivity of 85.7% and specificity of 61.9%. In patients over 50 years of age, low risk was prevalent (70.6%). The cutoff point for Ki67 by ROC curve adjustment was 33% (p=0.040), with sensitivity of 93.3% and specificity of 41.7%. For these cutoff points, the kappa coefficient of agreement was estimated at 0.29.Conclusions: Ki67 correlated with the Oncotype DX® recurrence score. The kappa index showed low agreement. The results suggest that Ki67 should not be used alone for therapeutic decision-making, but rather associated with clinical factors.
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NOGUEIRA SPALANZANI, REGIANE;
MUNIZ VASCONCELOS, THAÍS;
BÁVIA, LORENA;
SOUZA RODRIGUES, LUIZA;
MESA, DANY;
SIMONETI FONSECA, ALINE;
Cavalli, Luciane Regina;
Libera M. Dalla Costa
Palavra-chave:
Intestinal dysbiosis;
microbiome;
oportunistic infections
Áreas do conhecimento:
Ciências Biológicas; Microbiologia; Biologia e Fisiologia dos Microorganismos; Virologia;
Ciências Biológicas; Microbiologia; Microbiologia Médica;
Ciências da Saúde; Medicina; Microbiologia; Biologia Molecular
resumo ...
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Luciana de Alcântara Nogueira;
RAIZA CAROLINE NORA LINARES;
Camila Pereira dos Santos;
Maria de Fatima Mantovani;
Jacqueline Munhoes dos Santos Soares;
Sonia Silva Marcon;
Elis Cristina Marques;
Luciana Puchalski Kalinke
Revista UniVap,
v. 31,
n. 72,
p. 1-11,
2025
Palavra-chave:
Saúde Coletiva;
saúde do trabalhador
Áreas do conhecimento:
Ciências da Saúde; Enfermagem
resumo ...
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Leonel dos Santos Silva;
Ana Paula Felicio de Lima;
Cleo WatanabePisaia;
Lourdes Maria Rosinski Lima Gomes;
NATALIA NAOME OSHIRO;
Paulo Ricardo Bittencourt Guimarães;
Luciana de Alcântara Nogueira;
Luciana Puchalski Kalinke
Palavra-chave:
Cuidados Paliativos;
Enfermagem oncológica;
Terapias não-farmacológicas
Áreas do conhecimento:
Ciências da Saúde; Enfermagem; enfermagem oncológica
resumo ...
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ANA ELIZABETH LOPES DE CARVALHO;
Jorge Vinícius Cestari Felix;
Jéssica de Oliveira Veloso Vilarinho;
Luciana Puchalski Kalinke;
MARCIA BUCCO;
Nilton Orlando da Silva
Palavra-chave:
Competência profissional;
simulação clínica;
Segurança do paciente
Áreas do conhecimento:
Ciências da Saúde; Enfermagem; Enfermagem em Saúde do Adulto e do Idoso
resumo ...
ABSTRACT Objectives: to develop and validate a model for designing clinical simulation scenarios...
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TEIXEIRA, CAROLYNNE MARTINS;
BRESSAN, JOSEFINA;
JUVANHOL, LEIDJAIRA LOPES;
LEAL, ARIETA CARLA GUALANDI;
Adriano Marçal Pimenta;
HERMSDORFF, HELEN HERMANA MIRANDA
Palavra-chave:
Food consumption;
Obesity;
Vitamins;
Cohort studies
Áreas do conhecimento:
Ciências da Saúde; Enfermagem; Análise Nutricional de População;
Ciências da Saúde; Enfermagem; Epidemiologia;
Ciências da Saúde; Saúde Coletiva
resumo ...
DNA methylation is labile to the consumption of methyl donor nutrients (MetD), and may modulate gene expression associated with obesity. To evaluate the association between MetD consumption and the incidence of obesity, as well as to test the modifying role of the effect of the family history of the disease in this association. This longitudinal study, with 1205 participants of the Cohort of Universities of Minas Gerais (CUME study), evaluated the incidence of obesity in a 4-year follow-up (2016– 2020). The intake of MetD nutrients (B2, B6, B9, B12, choline, betaine, and methionine) was estimated through a semi-quantitative food frequency questionnaire validated for the population. A MetD score was calculated and later stratified into low, intermediate, and high scores according to the tertiles of the sample. The presence of father and mother with obesity and parental obesity (father and mother with the disease) was self-reported. Associations were tested by Cox regression. 89 (7.4%) cases of obesity were identified during follow-up. Participants who were in the third quartile of B2 consumption and the second quartile of B9 and choline consumption presented 60% (95%CI: 0.20–0.79), 52% (95%CI: 0.26–0.89) and 52% (95%CI: 0.24–0.93) less risk of developing obesity, respectively. Presenting an intermediate MetD score was also associated with a lower risk for the outcome (HR: 0.40; 95%CI: 0.18–0.84). However, the association between high MetD score and obesity incidence was observed only among individuals with a history of the disease in the father (HR: 0.19; 95%CI: 0.03–0.98; p-interaction = 0.022). Intermediate consumption of B2, B9, and choline was associated with a lower risk of obesity, while a high MetD score was associated with reduced risk of outcome in those with a history of paternal obesity.
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Ivan Toshio Maruo;
Ricardo Moresca;
Aguinaldo Coelho de Farias;
Armando Yukio Saga;
Hiroshi Maruo
ORTHO SCIENCE: ORTHODONTIC SCIENCE AND PRACTICE,
v. 18,
p. 20
2025
Palavra-chave:
contenção;
ortodontia
Áreas do conhecimento:
Ciências da Saúde; Odontologia; Ortodontia
resumo ...
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