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Publicações - ciências biológicas

p.Phe508del , p.Gly542X , p.Arg1162X , p.Asn1303Lys , and p.Lys683serfsX38 mutations in CF newborn screening of Brazilian children RIBAS, D.I.R.; ESCALIANTE, C.H.; BORTOLI, C.G.; DE OLIVEIRA, C.R.F.; Liya Regina Mikami; RIEDI, C.A.; RASKIN, S.; ROSÁRIO FILHO, NELSON A.; PEREIRA-FERRARI, L. Clinical Genetics, v. 1, p. 1 2017 DOI Palavra-chave: cystic fibrosis Áreas do conhecimento: Ciências da Saúde; Medicina; Clínica Médica; Pneumologia; Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética resumo ...
Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after subchronic exposure GUILOSKI, I.C.; DE ASSIS, HELENA CRISTINA SILVA; RIBAS, JOÃO LUIZ COELHO; Laercio Piancini; DAGOSTIM, ANA CAROLINA; CIRIO, SILVANA MARIS; FÁVARO, LUIS FERNANDO; Boschen, Suelen Lucio; Cestari, M.M.; DA CUNHA, CLÁUDIO ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, v. 53, p. 111-120, 2017 DOI Palavra-chave: ensaio cometa; ensaio cometa no fígado; Genotoxicidade Áreas do conhecimento: Ciências Biológicas; Genética; Genotoxicidade em Peixes; Ciências Biológicas; Genética; Genética Animal; Mutagênese Ambiental resumo ...
Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after subchronic exposure GUILOSKI, I.C.; Helena Cristina da Silva de Assis; RIBAS, JOÃO LUIZ COELHO; PIANCINI, LAERCIO DANTE STEIN; DAGOSTIM, ANA CAROLINA; CIRIO, SILVANA MARIS; FÁVARO, LUIS FERNANDO; Boschen, Suelen Lucio; Cestari, M.M.; DA CUNHA, CLÁUDIO ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, v. 53, p. 111-120, 2017 DOI Palavra-chave: Toxicologia ambiental Áreas do conhecimento: Ciências Biológicas; Ecologia; Ecologia Aplicada resumo ...
Paralarvae of Octopus vulgaris Type II are stenohaline conformers: relationship to field distribution and dispersal CASTELLANO, GIOVANNA CARSTENS; DA VEIGA, MARCOS PAULO TRINDADE; MAZZINI, FABRICIO STRUFALDI; VIDAL, ERICA A. G.; Carolina Arruda de Oliveira Freire HYDROBIOLOGIA, v. 808, p. 71-82, 2017 DOI Palavra-chave: Octopus; paralarva; osmoconformador; NPS Áreas do conhecimento: Ciências Biológicas; Fisiologia Comparada; Fisiologia Comparativa da Osmorregulação resumo ... The degree of euryhalinity of cephalopod planktonic paralarvae potentially affects the dispersal capacity and distributional range of species. Herein, we tested the hypothesis that O. vulgaris Type II paralarvae would show some tolerance to seawater dilution, evaluated from integrated field and laboratory experiments. Paralarvae were collected from zooplankton samples (salinities of 30.3–32.6), in the Paraná Bay Estuarine Complex (PBEC), Southern Brazil. In the laboratory, they were exposed to salinities of 28, 30, 33, 35 (control), and 37, from 15 min to 24 h. Survival ranged from 60 to 83%, 73–100%, and 100% at salinity of 28, 30, and 33–37, respectively. Body fluid osmolality (BFO), body water content (BWC), and ninhydrin-positive substances (NPS, amino acids) were quantified at salinities of 33, 35, and 37 (with 100% survival). BFO was always isosmotic to the external medium. BWC and the high NPS concentration remained unchanged in all salinities. Thus, these paralarvae tolerate some deviation from seawater salinity, displaying osmoconforming behavior, maintain body hydration, and show high ability of tissue volume/water regulation in short periods of time. Presumably, this physiological capacity of paralarvae might be one factor allowing their dispersal and survival along environments with moderate deviations from seawater salinity.
Past connection and isolation of catchments: The sea-level changes affect the distribution and genetic variability of coastal freshwater fishes TSCHÁ, MARCEL K.; BACHMANN, LUTZ; ABILHOA, VINÍCIUS; Walter Antonio Boeger ESTUARINE COASTAL AND SHELF SCIENCE, v. 190, p. 31-39, 2017 DOI Palavra-chave: Evolution; Stockholm paradigm; filogeografia; Biogeografia Áreas do conhecimento: Ciências Biológicas; Evolução resumo ...
Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes SLOMP, AMANDA M.; Maria Eugênia R. Duarte; Miguel Noseda; OTUKI, MICHEL F.; Alan Guilherme Gonçalves; Barreira, Sandra M.W.; CARRENHO, LUISE Z.B.; VANDRESEN, CAMILA C.; ZATTONI, INGRID F.; Ló, Stephanie M.S.; DALLAGNOL, JULIANA C.C.; Diogo R. B. Ducatti; ORSATO, ALEXANDRE Bioorganic & Medicinal Chemistry Letters (Print), v. 27, n. 2, p. 156-161, 2017 DOI Palavra-chave: Photodynamic therapy; Porphyrins; keratinocytes Áreas do conhecimento: Ciências Biológicas; Biotecnologia resumo ...
Photodynamic effect of meso-(aryl)porphyrins and meso-(1-methyl-4-pyridinium)porphyrins on HaCaT keratinocytes SLOMP, AMANDA M.; DUARTE, M. EUGÊNIA R.; NOSEDA, MIGUEL D.; OTUKI, M; GONÇALVES, ALAN G.; Barreira, Sandra M.W.; CARRENHO, LUISE Z.B.; VANDRESEN, CAMILA C.; ZATTONI, INGRID F.; Ló, Stephanie M.S.; DALLAGNOL, JULIANA C.C.; DUCATTI, DIOGO R.B.; ORSATO, ALEXANDRE Bioorganic & Medicinal Chemistry Letters (Print), v. 27, n. 2, p. 156-161, 2017 DOI Palavra-chave: HaCaT keratinocytes; Photodynamic therapy; Photosensitizer; Porphyrins; psoriasis Áreas do conhecimento: Ciências Biológicas; Patofisiologia e farmacologia de processos inflamatórios cutâneos resumo ...
Phylogenomic relationship of feijoa (Acca sellowiana (O.Berg) Burret) with other Myrtaceae based on complete chloroplast genome sequences MACHADO, LILIAN DE OLIVEIRA; VIEIRA, LEILA DO NASCIMENTO; STEFENON, VALDIR MARCOS; OLIVEIRA PEDROSA, FÁBIO DE; Emanuel Maltempi de Souza; GUERRA, MIGUEL PEDRO; NODARI, RUBENS ONOFRE Genetica ('s-Gravenhage), v. 145, n. 2, p. 163-174, 2017 DOI Palavra-chave: chloroplast sequencing; feijoa; Phylogeny Áreas do conhecimento: Ciências Biológicas; Biologia Molecular resumo ... Given their distribution, importance, and richness, Myrtaceae species comprise a model system for studying the evolution of tropical plant diversity. In addition, chloroplast (cp) genome sequencing is an efficient tool for phylogenetic relationship studies. Feijoa [Acca sellowiana (O. Berg) Burret; CN: pineapple-guava] is a Myrtaceae species that occurs naturally in southern Brazil and northern Uruguay. Feijoa is known for its exquisite perfume and flavorful fruits, pharmacological properties, ornamental value and increasing economic relevance. In the present work, we reported the complete cp genome of feijoa. The feijoa cp genome is a circular molecule of 159,370 bp with a quadripartite structure containing two single copy regions, a Large Single Copy region (LSC 88,028 bp) and a Small Single Copy region (SSC 18,598 bp) separated by Inverted Repeat regions (IRs 26,372 bp). The genome structure, gene order, GC content and codon usage are similar to those of typical angiosperm cp genomes. When compared to other cp genome sequences of Myrtaceae, feijoa showed closest relationship with pitanga (Eugenia uniflora L.). Furthermore, a comparison of pitanga synonymous (Ks) and nonsynonymous (Ka) substitution rates revealed extremely low values. Maximum Likelihood and Bayesian Inference analyses produced phylogenomic trees identical in topology. These trees supported monophyly of three Myrtoideae clades.
PHYLOGENY AND ECOLOGY ILLUMINATE THE EVOLUTION OF ASSOCIATIONS UNDER THE STOCKHOLM PARADIGM: AGLAIOGYRODACTYLUS SPP.(GYRODACTYLIDAE, MONOGENOIDEA) AND SPECIES OF LORICARIIDAE (ACTINOPTERYGII, SILURIFORMES) Patella, L; Daniel R Brooks; Walter Antonio Boeger VIE ET MILIEU-LIFE AND ENVIRONMENT, v. 67, n. 2, p. 91-102, 2017 Home page Palavra-chave: coevolution; MONOGENOIDEA Áreas do conhecimento: Ciências Biológicas; Evolução resumo ...
Phylogeny and evolution of the genus Ctenocolum Kingsolver & Whitehead (Coleoptera, Chrysomelidae, Bruchinae), with the description of three new species Daiara Manfio; ISAAC REIS JORGE; Gael Kergoat; Cibele Stramare Ribeiro-Costa INSECT SYSTEMATICS & EVOLUTION, p. 1-35, 2017 DOI Palavra-chave: Taxonomy; Cladistics; Seed beetles Áreas do conhecimento: Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes; Ciências Biológicas; Zoologia; Morfologia dos Grupos Recentes resumo ... The seed beetle genus Ctenocolum Kingsolver & Whitehead is peculiar because its preferred host Lonchocharpus Kunth (Fabaceae) is not preyed upon by other bruchine species. This study investigates the phylogenetic relationships and evolution of this genus and of its species groups, while providing the description of three new species and of the male of C. biolleyi Kingsolver & Whitehead. To infer phylogenetic relationships, a character matrix of 40 morphological characters was assembled and analysed using both parsimony and Bayesian inference. Ancestral state estimations of host plant use and biogeography analyses were also performed. A total of 22 species were examined: 16 Ctenocolum species (including the three new ones) and six outgroup bruchine species (from genera Caryedes Hummel, Meibomeus Bridwell, Pygiopachymerus Pic and Pachymerus Thunberg). All resulting trees support the monophyly of the genus Ctenocolum. Three synapomorphies characterize the genus: (i) head with frontal carina enlarged at base, (ii) male pygidium truncated apically, and (iii) lateral lobes of tegmen with dorsal process. The two known species groups are also recovered monophyletic in the parsimony analyses. The following three species are described: Ctenocolum inmaculatus Manfio & Ribeiro-Costa sp. nov. (Type locality: Venezuela, Guarico), which belongs to the group tuberculatum; Ctenocolum nigronotus Manfio & Ribeiro-Costa sp. nov. (Type locality: Porto Rico, Mayaguez) and C. pallidus Manfio & Ribeiro-Costa sp. nov. (Type locality: Republic of Guyana), which belong to the group podagricus. Finally, we present colored illustrations of dorsal patterns and male genitalia for these three new species and C. biolleyi in addition to an updated key for the genus Ctenocolum.

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