Publicações - ciências biológicas


ALVES-ARAÚJO, ANDERSON; TULER, AMÉLIA; AMORIM, ANDRÉ; MOREIRA, ANDRÉ; COSENZA, BRAZ; SOSSAI, BRENNO; SILVA, CHRISTIAN; LOPES, CLAUDIA; MONTEIRO, DANIELE; COUTO, DAYVID; LIMA, DUANE; MOREIRA, MARINA; DALCIN, EDUARDO; RAMOS, ELIANA; LÍRIO, ELTON; SALIMENA, FÁTIMA; DE OLIVEIRA, FELIPE; FRAGA, FERNANDA; TORRES-LEITE, FILIPE; ANTAR, GUILHERME; SHIMIZU, GUSTAVO; LIMA, HAROLDO; CARRIJO, TATIANA; MEDEIROS, HERISON; LUBER, JAQUELINI; CHRIST, JHENIFFER; LANNA, JOÃO; ZORZANELLI, JOÃO PAULO; FREITAS, JOELCIO; PASTORE, JOSÉ; MELO, JOSÉ; PAULA-SOUZA, JULIANA; OLIVEIRA, JULIANA; LOHMANN, LÚCIA; PEDERNEIRAS, LEANDRO; FREITAS, LEANDRO; GIACOMIN, LEANDRO; MEIRELES, LEONARDO; SILVA, LUIS; PINTO, LUIZ; MENINI NETO, LUIZ; TROVÓ, MARCELO; GARBIN, MÁRIO; MORIM, MARLI; LOBÃO, ADRIANA; RIBEIRO, MICHEL; PENA, NELSON; LABIAK, PAULO; CARDOSO, PEDRO; VIANA, PEDRO; MORAES, PEDRO; MORAES, QUÉLITA; ZORZANELLI, RAQUEL; AMARAL, RENARA; ASPRINO, RENATA; SCHEIDEGGER, ALANA; Renato Goldenberg; MAGNAGO, RICARDO; COUTO, RICARDO; DUTRA, SANDRINE; HOYOS-GÓMEZ, SAÚL; VIEIRA, TAMARA; FLORES, THIAGO; DUTRA, VALQUÍRIA; MIRANDA, VÍCTOR; MANHÃES, VITOR; FIRMINO, ALINE; FORZZA, RAFAELA; DE MELO SILVA, ALINE; NEPOMUCENO, ÁLVARO
BIODIVERSITY DATA JOURNAL, v. 10, p. e75910 2022 DOI
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The Atlantic Forest is one of the most threatened biomes in the world. Despite that, this biome still includes many areas that are poorly known floristically, including several protected areas, such as the "Floresta Nacional do Rio Preto" ("Flona do Rio Preto"), located in the Brazilian State of Espírito Santo. This study used a published vascular plant species list for this protected area from the "Catálogo de Plantas das Unidades de Conservação do Brasil" as the basis to synthesise the species richness, endemism, conservation and new species occurrences found in the "Flona do Rio Preto".The published list of vascular plants was based on field expeditions conducted between 2018 and 2020 and data obtained from herbarium collections available in online databases. Overall, 722 species were documented for the "Flona do Rio Preto", 711 of which are native to Brazil and 349 are endemic to the Atlantic Forest. In addition, 60 species are geographically disjunct between the Atlantic and the Amazon Forests. Most of the documented species are woody and more than 50% of these are trees. Twenty-three species are threatened (CR, EN and VU), while five are Data Deficient (DD). Thirty-two species are new records for the State of Espírito Santo. Our results expand the knowledge of the flora of the Atlantic Forest and provide support for the development of new conservation policies for this protected area.
KRETZSCHMAR, GABRIELA CANALLI; TARGA, ADRIANO D. S.; SOARES-LIMA, SHEILA COELHO; DOS SANTOS, PRISCILA IANZEN; RODRIGUES, LAIS S.; MACEDO, DANIEL A.; RIBEIRO PINTO, LUIS FELIPE; LIMA, MARCELO M. S.; Angelica Beate Winter Boldt
Genes, v. 13, n. 12, p. 2397 2022 DOI
Palavra-chave: Ácido Fólico; Vitamina B12; Doença de Parkinson; kinureninase; expressao gênica; metilação do DNA
Áreas do conhecimento: Ciências Biológicas; Epigenética; Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética
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Valéria Bumiller-Bini Hoch; Andre Franke; Claudia Pföhler; Margitta Worm; Nina van Beek; Matthias Goebeler; Miklós Sárdy; Saleh Ibrahim; Hauke Busch; Jennifer Elisabeth Hundt; Patrícia S A Souza; Ana Flávia Kohler; Petzl-Erler, Maria Luiza; danillo gardenal augusto; Sara Cristina Lobo-Alves; Danielle Malheiros; Gabriel Adelman Cipolla; Angelica Beate Winter Boldt; Karin Braun-Prado; Michael Wittig
Viruses-Basel, v. 14, p. 879 2022 DOI
Palavra-chave: pênfigo foliáceo; virus; polimorfismo; haplótipo; IRF8; TRIM5
Áreas do conhecimento: Ciências Biológicas; Genética Humana e Médica; Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética
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The long search for the environmental trigger of the endemic pemphigus foliaceus (EPF, fogo selvagem) has not yet resulted in any tangible findings. Here, we searched for genetic associations and the differential expression of host genes involved in early viral infections and innate antiviral defense. Genetic variants could alter the structure, expression sites, or levels of the gene products, impacting their functions. By analyzing 3063 variants of 166 candidate genes in 227 EPF patients and 194 controls, we found 12 variants within 11 genes associated with differential susceptibility (p < 0.005) to EPF. The products of genes TRIM5, TPCN2, EIF4E, EIF4E3, NUP37, NUP50, NUP88, TPR, USP15, IRF8, and JAK1 are involved in different mechanisms of viral control, for example, the regulation of viral entry into the host cell or recognition of viral nucleic acids and proteins. Only two of nine variants were also associated in an independent German cohort of sporadic PF (75 patients, 150 controls), aligning with our hypothesis that antiviral host genes play a major role in EPF due to a specific virus–human interaction in the endemic region. Moreover, CCL5, P4HB, and APOBEC3G mRNA levels were increased (p < 0.001) in CD4+ T lymphocytes of EPF patients. Because there is limited or no evidence that these genes are involved in autoimmunity, their crucial role in antiviral responses and the associations that we observed support the hypothesis of a viral trigger for EPF, presumably a still unnoticed flavivirus. This work opens new frontiers in searching for the trigger of EPF, with the potential to advance translational research that aims for disease prevention and treatment.
Breno Rodrigo de Araujo; Pinto, Ângelo P.; Ângelo Parise Pinto; Andre Padial
ECOHYDROLOGY, p. e2419 2022 DOI Home page
Palavra-chave: Coenagrionid; Damselfly; Dragonfly; Homogeneity; Libellulidae; metacommunity
Áreas do conhecimento: Ciências Biológicas; Ecologia; Ecologia de Ecossistemas; Ciências Biológicas; Ecologia; Ecologia Aplicada
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GOMES, LUCAS ROBERTO PEREIRA; ZAWADNEAK, MARIA APARECIDA CASSILHA; da Costa-Ribeiro, Magda Clara Vieira; JAREK, TIAGO MIGUEL; Cláudio J B Carvalho
Arthropod Systematics and Phylogeny, v. 80, p. 511-522, 2022 DOI
Palavra-chave: Brassicaceae; DNA barcode; Insect pest; plant?insect interaction; root maggot flies
Áreas do conhecimento: Ciências Biológicas; Brassicaceae
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MITCHELL, DAVID ALEXANDER; KRIEGER, NADIA
BIOCHEMICAL ENGINEERING JOURNAL, v. 178, p. 108276 2022 DOI
Palavra-chave: lipase; cinética enzimática; ping pong bi bi
Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Biotecnologia; Ciências Biológicas; Bioquímica; cinética enzimática
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Valéria Bumiller-Bini Hoch; Larissa Schneider; Anna Elisabeth Pumpe; Emelie Lüders; Jennifer Elisabeth Hundt; Angelica Beate Winter Boldt
Life-Basel, v. 12, n. 3, p. 329 2022 DOI
Palavra-chave: via imunogênica de morte celular; Apoptose; necroptose; pênfigo foliáceo; Pênfigo Vulgar; acantólise
Áreas do conhecimento: Ciências Biológicas; Biologia Molecular; Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética
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BAYER, HUGO; Cristina Aparecida Jark Stern; TROYNER, FERNANDA; GAZARINI, L; GUIMARAES, FRANCISCO S.; Leandro José Bertoglio
NEUROPHARMACOLOGY, v. 205, p. 108913-11, 2022 DOI
Palavra-chave: canabidiol; Condicionamento; Córtex pré-frontal; Extinção; psicofarmacologia; Reativação da memória
Áreas do conhecimento: Ciências Biológicas; Farmacologia; Neuropsicofarmacologia
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DZUMAN, MARIA JUDITE; SEVERO, IHANA AGUIAR; MOREIRA, MICHELLE APARECIDA COELHO; DE LIMA LUZ JUNIOR, LUIZ FERNANDO; MITCHELL, DAVID ALEXANDER; Jóse Viriato Coelho Vargas; MARIANO, ANDRÉ BELLIN
BioEnergy Research, v. 15, p. s12155-022-1039 2022 DOI
Palavra-chave: Extraction of lipids; dry biomass production
Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia
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The reuse of the culture media after biomass growth can be a cost-effective strategy for large-scale microalgae production, especially when the target product is biofuel. Therefore, this study aimed to investigate the effect of recycling the microalgae Tetradesmus obliquus culture medium, focusing on the improved production of biomass and lipids, biodiesel properties, and cost reduction. The experiments were carried out in duplicate and three sequential steps with successive recycling (50% of the clarified medium and 50% of the standard). It was found that cells from recycled cultures had a similar overall performance as those from the fresh medium (standard). From this verification, the main findings of this research pointed out that (i) the consumption of the nutrients was efficient, with values in the order of 99% nitrate, 20% phosphate, 64% total iron, and 9% potassium; (ii) the average contents of biomass and lipids in the recycled medium increased around 20% to 24%, respectively, concerning the standard; (iii) the polyunsaturated fatty acids pool present in the microalgal oil dropped from 20.71 to 9.78% in the recycled culture, which represents a high-quality feedstock for biofuel; and (iv) the biodiesel properties evaluated, including iodine and saponification values, were 48&nbsp;g I2 100&nbsp;g−1 and 254&nbsp;mg KOH/goil−1, respectively. Finally, this recyclability bioprocess can reduce overall costs by about 34%, thus improving the economic viability of microalgae production.
CARVALHO, TAMYRES MINGORANCE; CARVALHO DE OLIVEIRA, JAQUELINE; Daniela Fiori Gradia; RIBEIRO, ENILZE MARIA DE SOUZA FONSECA; BRASIL, GUILLERMO ORTIZ; JUCOSKI, TAYANA SCHULTZ; ADAMOSKI, DOUGLAS; LIMA, RUBENS SILVEIRA DE; SPAUTZ, CLEVERTON C.; ANSELMI, KARINA FURLAN; OZAWA, PATRICIA MIDORI MUROBUSHI; CAVALLI, IGLENIR JOÃO
Frontiers in Genetics, v. 13, p. 1 2022 DOI
Palavra-chave: Breast cancer; miR-142-5p; miR-150-5p; miR-320a; miR-4433b-5p; Biomarkers
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