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Publicações - ciências da saúde

Óleo de Prímula Como Suplemento Alimentar Marcela santos Ferreira; Kelli Daiane Camargo Rocha; MN Rocha Brazilian Journal of Development, v. 8, n. 5, p. 41440-41455, 2022 DOI Home page Palavra-chave: Anti-inflamatório; gama-linolênico; lipídeos; omega Áreas do conhecimento: Ciências da Saúde; Farmácia; Atenção Farmacêutica; Ciências da Saúde; Farmácia; Farmácia clínica, assistência e atenção farmacêuticas; Ciências da Saúde; Nutrição; Desnutrição e Desenvolvimento Fisiológico resumo ...
Patient-perceived barriers to surgical treatment of cleft lip and palate in Brazil- A multi-region study CITRON, ISABELLE; Renato S. Freitas; DE ANDRADE SÁ, ÁLVARO JÚLIO; ROCHA, FRANKLIN; COLLARES, MARCUS VINICIUS; ALONSO, N.; BATISTA, JOAO; COSTA, EMANOEL; LIMA, CAETANO; ISE, ANANDA; MENEZES, CAMILA; ROA, LINA; SALUJA, SAURAB; STAFFA, STEVEN J. Journal of Plastic Reconstructive and Aesthetic Surgery, v. 1, p. 1 2022 DOI Palavra-chave: fissura lábio palatina Áreas do conhecimento: Ciências da Saúde; Farmacologia; Transmissão Neuromuscular resumo ...
Perfil da dor lombar em trabalhadores dos restaurantes de uma universidade pública do sul do Brasil Fernanda Vargas Lima; Luiza Grassmann Dias; Phillipe Augusto Brun Bette; Arlete Ana Motter; Ana Carolina Brandt de Macedo; Talita Gianello Gnoato Zoltz O MUNDO DA SAÚDE (CUSC. IMPRESSO), v. 46, p. 483-492, 2022 DOI Palavra-chave: lombalgia; medição da dor; saúde do trabalhador; Amplitude de Movimento Articular Áreas do conhecimento: Ciências da Saúde; Fisioterapia preventiva; Ciências da Saúde; Fisioterapia e Terapia Ocupacional; Ergonomia resumo ...
Physical exercise influences astrocytes in the striatum of a Parkinson?s disease male mouse model Louise Caroline Vitorino; Karla Ferreira Oliveira; Wagner Antonio Barbosa da Silva; Carlos Augusto B.A. Gomes; Luciana Ferreira Romão; Silvana Allodi; Cynton Lourenço Corrêa NEUROSCIENCE LETTERS, n. C, p. 136466-136473, 2022 DOI Palavra-chave: Doença de Parkinson; Células da glia; Exercício; modelo animal Áreas do conhecimento: Ciências da Saúde; Fisioterapia neurofuncional resumo ...
Physiological and ankle functions are discriminating factors for the risk of falls in women in treatment of osteoporosis Renata Gonçalves Pinheiro Corrêa; Anna Raquel Silveira Gomes; BORBA, VICTÓRIA ZEGHBI COCHENSKI International Journal of Environmental Research and Public Health, v. 19, p. 12643 2022 DOI Palavra-chave: elderly; osteoporosis; intrinsic factors; falls; fractures; treatment Áreas do conhecimento: Ciências da Saúde; Farmacologia; Transmissão Neuromuscular; Ciências da Saúde; Medicina; Clínica Médica; Nefrologia resumo ...
Polybrominated diphenyl ethers BDE-47 and BDE-99 modulate murine melanoma cell phenotype in vitro STEIL, GISLEINE JARENKO; BUZZO, JOÃO LUIZ ALDINUCCI; C A Oliveira Ribeiro; Filipak Neto, Francisco Environmental Science and Pollution Research, v. 29, n. 8, p. 11291-11303, 2022 DOI Palavra-chave: Polibromados; BDE - 209; BDE-47; Melanoma; Estudo in vitro Áreas do conhecimento: Ciências Biológicas; Ecologia Aplicada; Ecotoxicologia; Ciências da Saúde; Saúde Coletiva; Saúde Pública resumo ... Cancer is one of the leading causes of mortality worldwide. Even with the advances of pharmaceutical industry and treatments, the mortality rate for various types of cancer remains high. In particular, phenotypic alterations of tumor cells concerning drug efflux, migratory and invasive capabilities may represent a hurdle for cancer treatment and contribute to poor prognosis. In the present study, we investigated the effects of polybrominated diphenyl ethers (PBDEs) used as flame retardants on phenotypic features of melanoma cells that are important for cancer. Murine melanoma B16-F1 (less metastatic) and B16-F10 (more metastatic) cells were exposed to 0.01–1.0 nM of BDE-47 (2,2′,4,4′-tetrabromodiphenyl ether), BDE-99 (2,2′,4,4′,5-pentabromodiphenyl ether), and the mixture of both (at 0.01 nM) for 24 h (acute exposure) and 15 days (chronic exposure). The polybrominated diphenyl ethers (PBDEs) did not affect cell viability but led to increased drug efflux transporter activity, cell migration, and colony formation, as well as overexpression of Abcc2 (ATP-binding cassette subfamily C member 2), Mmp-2 (matrix metalloproteinase-2), Mmp-9 (matrix metalloproteinase-9), and Tp53 (tumor protein p53) genes and downregulation of Timp-3 (tissue inhibitor of metalloproteinase 3) gene in B16-F10 cells. These effects are consistent with increased aggressiveness and malignancy of tumors due to exposure to the flame retardants and raise some concerns on the effects such chemicals may have on melanoma treatment and cancer prognosis.
Pregnancy in Patients With Hereditary Angioedema and Normal C1 Inhibitor GABRIEL, NATALIA; PESQUERO, JOAO B.; Anete Sevciovic Grumach; MARCELINO, FERNANDA; FERRIANI, MARIANA P. L.; ARRUDA, L. KARLA; CAMPOS, RÉGIS A.; GONÇALVES, ROZANA F.; CHONG-NETO, HERBERTO; ROSÁRIO FILHO, NELSON A.; VALLE, SOLANGE O. R. Frontiers in Allergy, v. 3, p. 846968 2022 DOI Palavra-chave: angioedema hereditário resumo ... BackgroundHAE with normal C1 inhibitor (HAE-nC1-INH) has been identified as a bradykinin mediated angioedema. Estrogens are one of the main trigger factors. Pregnancy in HAE with C1 inhibitor deficiency showed variable course, however, few reports are available for HAE-nC1-INH. We evaluated the course of pregnancies in women diagnosed with HAE-nC1-INH.MethodsWomen with diagnosis of HAE-nC1-INH according to the following criteria: clinical manifestations similar to HAE-C1-INH, normal biochemical evaluation and family history were included. A questionnaire about pregnancies was applied after consent. Genetic evaluation for known mutations was performed in all patients.ResultsA total of 45 pregnancies occurring in 26 HAE-nC1-INH patients were evaluated (7/26 patients with F12 variant). Spontaneous abortion was reported in 8/45 (17.8%) pregnancies. Onset of attacks started before the pregnancy in 18/26 patients; during the pregnancy in 2/26; and after the pregnancy in 6/26. HAE attacks occurred in 24/37 pregnancies (64,7%): during the 1st trimester in 41.7%; 2nd trimester in 12.5%; 3rd trimester in 20.8%; 1st and 3rd trimesters in 4.2% and during the whole pregnancy in 20.8%. Among 15/18 patients who had attacks before pregnancy, symptoms persisted with worsening in 9/15; improvement in 4/15; no change in 1/15, and no response in 1/15.ConclusionsThe occurrence of abortion in HAE-nC1-INH was similar to the expected for not affected women. The 1st trimester of the pregnancy was ...
Preliminary Results of the Pharmacoepidemiological Study Pso.BRA Kaue Cesar Sa Justo; Aguinaldo Bonalumi Filho; Fernando Henrique Teixeira Zonzini; Jessica Scherer Dagostini; Adriane Reichert Faria; Anber Ancel Tanaka; CABRINI, D; JOÃO BATISTA CALIXTO; OTUKI, M International Journal of Physical Medicine & Rehabilitation, v. 10, n. 6, p. 1000653 2022 DOI Palavra-chave: Pharmacoepidemiology; psoriasis; Comorbidities Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia; Ciências da Saúde; Farmácia; Farmácia clínica, assistência e atenção farmacêuticas resumo ...
Primary syphilis presenting as oral lesion in a patient with HIV / AIDS: Case report of an unusual manifestation Isabella Eloy de Souza Barbaresco Damiani; Maria Ângela Naval Machado; Melissa Rodrigues Araujo; Antonio Adilson Soares de Lima Hiv & Aids Review, v. 21, n. 1, p. 83-87, 2022 DOI Palavra-chave: Dental care; HIV; HIV infections; Syphilis; Treponema Pallidum Áreas do conhecimento: Ciências da Saúde; Clínica Odontológica; Estomatologia resumo ...
PRODUÇÃO E PRODUTOS À BASE DE COCO (COCOS NUCIFERA L.): UMA REVISÃO / PRODUCTION AND PRODUCTS BASED ON COCONUT (COCOS NUCIFERA L.): A REVIEW Kelli Daiane Camargo Rocha; Marcela santos Ferreira; MN Rocha Brazilian Journal of Development, v. 8, n. 5, p. 41476-41491, 2022 DOI Home page Palavra-chave: Cocos nucifera L; copra; óleo de coco Áreas do conhecimento: CIENCIAS_AGRARIAS; Tecnologia de Alimentos; Ciências da Saúde; Farmácia; Bromatologia; Nutrição; Ciências da Saúde; Nutrição; Desnutrição e Desenvolvimento Fisiológico resumo ...

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