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Publicações - ciências biológicas

A Non-Toxic Binuclear Vanadium(IV) Complex as Insulin Adjuvant Improves the Glycemic Control in Streptozotocin-Induced Diabetic Rats LOPES, MATEUS S.; VALDAMERI, GLAUCIO; MOURE, VIVIAN R.; PICHETH, GERALDO; MANICA, GRACIELE C. M.; REGO, FABIANE G. M.; BAPTISTELLA, GABRIEL B.; NUNES, GIOVANA G.; FERREIRA, MATHEUS V.; Cunha, Joice M.; OLIVEIRA, KAUÊ MARCEL DE; ACCO, ALEXANDRA; LOPES, MARIA LUIZA C.; COUTO ALVES, ALEXESSANDER PHARMACEUTICALS, v. 17, n. 4, p. 486 2024 DOI Palavra-chave: diabetes Áreas do conhecimento: Ciências Biológicas; Farmacologia; Farmacologia Geral resumo ...
A Taxonomic Revision of the South American Trilobite Cockroaches of Parahormetica Brunner von Wattenwyl 1865 (Blattodea: Blaberidae), with Description of Parahormetica museunacional sp. nov. from the Atlantic Forest Leonardo Polizeli Aguiar; Pinto, Ângelo P.; Ângelo Parise Pinto NEOTROPICAL ENTOMOLOGY, v. 53, n. 2, p. electronic 2024 DOI Palavra-chave: Araucaria Forest; Blattaria; Blaberinae; New Species; Systematics; Zetoborinae Áreas do conhecimento: Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes; Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes resumo ... The taxonomically intricate genus of trilobite cockroaches, Parahormetica Brunner von Wattenwyl, 1865, is revised based on a comparative morphological analysis. The goals of this study are to review the nomenclature, propose hypotheses about specific delimitation, and provide diagnoses to allow identification of the taxonomic units in the genus. Based on the revised status of Parahormetica, we transferred Parahormetica hylaeceps Miranda-Ribeiro, 1936, and Parahormetica punctata Saussure, 1873, to the genus Bionoblatta Rehn, 1940. Therefore, the genus includes now four species of giant cockroaches which are predominantly distributed on the Atlantic Forest: Parahormetica bilobata (Saussure, 1864), Parahormetica cicatricosa Saussure, 1869, Parahormetica monticollis (Burmeister, 1838), and Parahormetica museunacional sp. nov. (holotype male deposited in DZUP: Brazil, Paraná). Diagnoses, key, distribution maps, images of living, non-type, and type specimens are made available. Our results make clear that the status and limits among Brachycolini genera pending a full revision.
Abstract 3681: Transcribed ultraconserved regions are associated with survival in multiple tumor types RODRIGUES, ANA CAROLINA; ADAMOSKI, DOUGLAS; Daniela Fiori Gradia; DE OLIVEIRA, JAQUELINE CARVALHO Cancer Research, v. 84, n. 6_Supplement, p. 3681-3681, 2024 DOI Palavra-chave: transcribed ultraconserved regions; cancer; Biomarkers Áreas do conhecimento: Ciências Biológicas; Genética; Genética Animal resumo ... Abstract. Ultraconserved regions (UCRs), encompassing 481 genomic segments identical across humans, mice, and rats, and conserved in other species, are distributed across all human chromosomes except 21 and Y. Over 90% of these regions, termed transcribed ultraconserved regions (T-UCRs) are expressed in at least one human tissue. Although extensively studied in the context of cancer since their discovery, the prognostic significance of T-UCRs in a pan-cancer context has not been explored. For this, TCGA data extracted from the TANRIC platform was utilized, differential expression and survival analysis was performed on different tumor types. Our analysis revealed that approximately 300 UCRs were expressed in the majority of the 20 tumor tissues. Additionally, it was noted that all examined tumor tissues expressed a higher number of UCRs compared to their non-tumor counterparts. Through t-distributed stochastic neighbor embedding (t-SNE) analysis, UCR expression patterns could distinguish primary tumor origins and types. Regarding the prognostic value, we identified 100 (20,8%) T-UCRs associated with disease-specific survival (DSS) and 102 (21.2%) T-UCRs associated with progression-free interval (PFI). Those T-UCRs are particularly important in the survival outcomes of kidney renal clear cell carcinoma (KIRC) and low-grade gliomas (LGC). In addition, we verified that uc.44, uc.48, uc.135, uc.144, uc.153, uc.217, uc.255, uc.256, uc.344, uc.357, uc.390, uc.427 and uc.436 were associated with survival of more than one tumor. Particularly, uc.135 high expression was associated with poor prognosis in Kidney Renal Papillary Cell Carcinoma (KIRP) and LGC, and good prognosis in KIRC. Uc.135 are mapped on MECOM gene, coding an oncoprotein acting as transcriptional regulator and involved in apoptosis, proliferation, and cell differentiation. Our findings suggest that analysis of T-UCRs expression have the potential to be used as predictive biomarkers and can help in studying the mechanisms and specific roles of the highlighted T-UCRs in cancer.Citation Format: Ana Carolina Rodrigues, Douglas Adamoski, Daniela F. Gradia, Jaqueline Carvalho de Oliveira. Transcribed ultraconserved regions are associated with survival in multiple tumor types [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 3681.
Additional Typifications of Ferns in the Guianas and New Types Added Michel Boudrie; Jefferson Prado AMERICAN FERN JOURNAL, v. 114, n. 3, p. 185-192, 2024 DOI Palavra-chave: Guianas; Guyana; Suriname; French Guiana; Lectotypifications Áreas do conhecimento: Ciências Biológicas; Botânica; Taxonomia Vegetal; Taxonomia de Criptógamos resumo ...
Alterations in neurotransmitters, steroid hormones, vitellogenin, and antioxidant system induced by di-n-butyl phthalate and di-isopentyl phthalate on catfish Rhamdia quelen GUILOSKI, I.C.; STERN, CRISTINA APARECIDA JARK; MARTINO-ANDRADE, ANDERSON JOEL; LEME, DANIELA MORAIS; SILVA DE ASSIS, HELENA CRISTINA; Cestari, M.M.; Taynah Vicari; VICENTINI, MAIARA; OYA-SILVA, LAÍS FERNANDA; CARVALHO, LUCICLEIDE ÂNGELO SILVA JUNGLES; DEDA, BRUNA; MARCONDES, FELLIP RODRIGUES; SIMEONI, RAFAEL DIAS; DE OLIVEIRA GUAITA, GISELE Environmental Science and Pollution Research, v. 31, n. 39, p. 51954-51970, 2024 DOI Palavra-chave: peixe; jundiá; Disruptor Endocrino; Hormônios em Peixes; vitelogenina Áreas do conhecimento: Ciências Biológicas; Farmacologia; Disrupção Endócrina; Ciências Biológicas; Farmacologia; Genotoxicidade em Peixes resumo ...
Alterations in neurotransmitters, steroid hormones, vitellogenin, and antioxidant system induced by di-n-butyl phthalate and di-isopentyl phthalate on catfish Rhamdia quelen GUILOSKI, IZONETE CRISTINA; Cristina Aparecida Jark Stern; MARTINO-ANDRADE, ANDERSON JOEL; LEME, DANIELA MORAIS; SILVA DE ASSIS, HELENA CRISTINA; CESTARI, MARTA MARGARETE; VICARI, TAYNAH; VICENTINI, MAIARA; OYA-SILVA, LAÍS FERNANDA; CARVALHO, LUCICLEIDE ÂNGELO SILVA JUNGLES; DEDA, BRUNA; MARCONDES, FELLIP RODRIGUES; SIMEONI, RAFAEL DIAS; DE OLIVEIRA GUAITA, GISELE Environmental Science and Pollution Research, v. 1, p. 1-17, 2024 DOI Áreas do conhecimento: Ciências Biológicas; Farmacologia; Toxicologia; Toxicologia Ambiental resumo ...
Alternativas protéticas para pacientes edêntulos com doença de Alzheimer Karina Massocatto Borsatto; Yasmine Mendes Pupo; Marcos André Kalabaide Vaz; Marcos André Kalabaide Vaz; FRANCO, ANA PAULA GEBERT DE OLIVEIRA REVISTA GESTÃO & SAÚDE (CURITIBA), v. 26, n. 2, p. 516-527, 2024 Palavra-chave: doença de Alzheimer; prótese dentária; reabilitação oral Áreas do conhecimento: Ciências Biológicas; Biologia Geral; odontologia; prótese dentária; Ciências Biológicas; Biologia Geral; odontologia; prótese dentária resumo ...
An overview of the Brazilian Chrysomelidae (Insecta: Coleoptera): the most species-rich beetle family in Brazil Adelita Maria Linzmeier; Luciano de A. Moura; Cibele Stramare Ribeiro-Costa; Daiara Manfio; Agrain, F.; Maria L. Chamorro; MORSE, GEOFFREY E.; Renato Regalin; Luká? Sekerka Zoologia, v. 41, p. 1-21, 2024 DOI Palavra-chave: leaf beetles; Brazilian fauna; biodiversity Áreas do conhecimento: Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes; Ciências Biológicas; Zoologia; Biodiversidade; Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes resumo ...
Anaesthetic Effect of Clove Basil (Ocimum gratissimum) Essential Oil on Macrobrachium rosenbergii Post-Larvae DE SOUZA VALENTE, CECÍLIA; MENDES, ARIELLY FÁVARO; DO NASCIMENTO FERREIRA, CAIO HENRIQUE; BALDISSEROTTO, BERNARDO; HEINZMANN, BERTA MARIA; André Martins Vaz dos Santos; Eduardo Luis Cupertino Ballester Aquaculture Journal, v. 4, n. 3, p. 192-202, 2024 DOI Palavra-chave: Aquaculture; Crustacean welfare; decapod anaesthesia; giant river prawn; Plant-derived anaesthetic Áreas do conhecimento: CIENCIAS_AGRARIAS; Tecnologia de Alimentos; Ciências Biológicas; Zoologia; Zoologia Aplicada; Conservação das Espécies Animais resumo ... This study evaluated the anaesthetic potential of clove basil (Ocimum gratissimum) essential oil (EO-OG) in the post-larvae (PLs) of M. rosenbergii. The PLs were individually transferred to aquariums (500 mL) containing 50, 100, 150, 200, or 300 μL L−1 EO-OG. A sixth group of PLs was exposed to freshwater only, and a seventh group was exposed to the highest concentration of ethanol used to dilute EO-OG. Upon reaching the anaesthesia stage, the PLs were transferred to aquariums (500 mL) with freshwater only to evaluate the recovery time. The shortest sedation times were observed at 200 (15.98 s) and 300 μL L−1 (25.85 s). The shortest anaesthesia time was observed at 200 μL L−1 (22.52 s). The longest recovery time was observed at 100 μL L−1 (1367.10 s); the shortest recovery time was observed at 150 μL L−1 (630.10 s). No mortality or adverse effects were observed in any experimental group. The concentration of 150 μL L−1 resulted in sedation (49.24 s), anaesthesia (80.10 s), and recovery (630.10 s) times within those suggested as adequate for freshwater prawn farming. This research demonstrated the sedative and anaesthetic properties of EO-OG and its potential application in prawn farming. This study recommends using 150 μL L−1 of EO-OG in M. rosenbergii PLs.
Antinociceptive and anti-inflammatory activity of extracts and α-pyrones isolated from Cantinoa stricta BARBOSA, FELIPE LUKACIEVICZ; EHRENFRIED, CARLOS AUGUSTO; RADULSKI, DÉBORA RASEC; OLIVEIRA, CRISTHIAN SANTOS; Stefanello, Maria Élida Alves; Aleksander Roberto Zampronio INFLAMMOPHARMACOLOGY, v. 32, n. 2, p. 1263-1275, 2024 DOI Palavra-chave: Cantinoa; constituintes químicos; atividade anti-inflamatória; Atividade analgésica Áreas do conhecimento: Ciências Exatas e da Terra; Química; Química Orgânica; Química dos Produtos Naturais; Ciências Biológicas; Farmacologia; Farmacologia Geral resumo ...

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