Publicações - ciências biológicas
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Daniela Ciccarelli;
Cleusa Bona
Palavra-chave:
coastal dunes vegetation;
plant anatomy;
plant functional trait
Áreas do conhecimento:
Ciências Biológicas; Botânica; ecologia vegetal;
Ciências Biológicas; Botânica; Morfologia Vegetal; Anatomia Vegetal
resumo ...
Coastal dunes are characterised by strong interactions between biotic and abiotic factors along a short gradient from the shoreline to the inland region. We carried out an ecological analysis of the vegetation in a protected area of the Italian coast to evaluate the relationships among species abundance, the occurrence of morphoanatomical traits related to leaves, stems, and roots, and soil variables. Three transects were established perpendicular to the shoreline, with 27 plots distributed in the frontal dunes, backdunes, and temporarily wet dune slacks. An analysis based on community-weighted mean values showed that the pioneer communities of the frontal dunes were dominated by ruderals that are well adapted to the harsh ecological conditions of these environments, showing succulent leaves, high limb thickness values, and low values for leaf dry matter content (LDMC). The backdune vegetation was a mosaic of annual herbaceous and perennial shrub communities showing both ruderal and stress-tolerant strategies (clonality, sclerified leaves, high LDMC values, root phenolics) consistent with less extreme ecological conditions. The dune slack areas were dominated by plants showing adaptations to both arid and flooded environments, such as C4 photosynthesis, amphistomatic leaves, and abundant aerenchyma in the roots. The invasive status, C4 photosynthesis, leaf trichomes, and aerenchyma in the roots were significantly correlated with soil humidity, organic matter content, and pH. These results demonstrate the usefulness of anatomical traits (including root system traits) in understanding the functional strategies adopted by plants. Invasive species tended to occupy plots with high levels of soil moisture, suggesting an avoidance strategy for the harsh environmental conditions of coastal sand dunes. Finally, we suggest including information regarding root systems into coastal monitoring programs because they are directly linked to soil parameters useful in coastal dune management and protection.
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RÓDIO, GRAZIELA RODRIGUES;
Isac George Rosset;
BRANDALIZE, ANA PAULA CARNEIRO
Palavra-chave:
Pesticidas;
Saúde
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia
resumo ...
(en)
Since the arrival of the first samples of pesticides in Brazil the tradings of these chemicals has only increased. Therefore, the population is exposed to various classes of pesticides throughout their lives. Considering this the present study aims to review the use of pesticides in brazilian cultures to demonstrate the importance of the population's knowledge and awareness about the consequences of the use of these products for public health. To do so data about the use of pesticides in agriculture and its consequences for the health of the population was collected through the use of descriptive-analytical-reflective methodology. Constant exposure to the various classes of pesticides represents a serious risk to public health, whether due to acute intoxications resulting from exposure to high concentrations in a short period, or to chronic intoxications resulting from contact with low concentrations for long periods. Even though agricultural workers and the population living around crops are more susceptible to the damage caused by these products, the consequences go beyond rural limits, reaching the entire population through food, water and air contaminated by these compounds. In conclusion it is necessary to increase researchs in this Field in order to understand the long-term consequences of the use of pesticides on health and the environment. It is also necessary to adjust surveillance actions in order to reduce the damage caused by the incorrect use of products as well to develop preventive and informative actions for all who use pesticides.
(es)
Desde la llegada de las primeras muestras de plaguicidas a Brasil, la comercialización de estos químicos solo ha aumentado. Por lo tanto, la población está expuesta a diversas clases de pesticidas a lo largo de su vida. Con esto en mente, el presente estudio tiene como objetivo revisar el uso de plaguicidas en las culturas brasileñas, así como demostrar la importancia del conocimiento y la conciencia de la población sobre las consecuencias del uso de estos productos para la salud pública. Para ello, se recolectaron datos sobre el uso de plaguicidas en la agricultura y sus consecuencias para la salud de la población, mediante el uso de metodología descriptiva-analítico-reflexiva. La exposición constante a las distintas clases de plaguicidas representa un grave riesgo para la salud pública, ya sea por intoxicaciones agudas, como resultado de la exposición a altas concentraciones en un período corto, o por intoxicaciones crónicas, derivadas del contacto con concentraciones bajas durante períodos prolongados. Si bien los trabajadores agrícolas y la población que vive alrededor de los cultivos son más susceptibles a los daños causados por estos productos, las consecuencias van más allá de los límites rurales, llegando a toda la población, a través de alimentos, agua y aire contaminados por estos compuestos. Se concluye que es necesario ampliar la investigación en el área para comprender las consecuencias a largo plazo del uso de plaguicidas sobre la salud y el medio ambiente. También es necesario adecuar las acciones de inspección con el fin de reducir los daños ocasionados por el uso inadecuado de los productos, así como desarrollar acciones preventivas e informativas para todos los usuarios de plaguicidas.
(pt)
Desde a chegada das primeiras amostras de agrotóxicos no Brasil a comercialização destes produtos químicos só vem aumentando. Por isso, a população encontra-se exposta a diversas classes de pesticidas por toda a vida. Tendo isso em vista, o presente trabalho objetiva revisar a utilização de agrotóxicos nas culturas brasileiras, bem como demonstrar a importância do conhecimento e conscientização da população acerca das consequências do uso destes produtos para a saúde pública. Para isso, realizou-se o levantamento de dados referente a utilização de defensivos na agricultura e suas consequências à saúde da população, através da utilização de metodologia descritiva-analítica-reflexiva. A exposição constante às diversas classes de agrotóxicos representa grave risco a saúde pública, seja por intoxicações agudas, resultantes da exposição a altas concentrações em um curto período, seja por intoxicações crônicas, decorrentes do contato com baixas concentrações por longos períodos. Muito embora os trabalhadores agrícolas e a população que vive ao redor das culturas sejam mais susceptíveis aos danos causados por estes produtos, as consequências ultrapassam os limites rurais, atingindo toda a população, através da contaminação de alimentos, água e ar contaminado por estes compostos. Conclui-se que é necessária a ampliação de pesquisas na área a fim de se entender as consequências da utilização de agrotóxicos a longo prazo à saúde e ao meio ambiente. É necessário também a adequação das ações fiscalizadoras, a fim de diminuir os danos causados pelo o uso indevido dos produtos, bem como desenvolver ações preventivas e informativas a todos que utilizam-se de defensivos.
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RUBIO-VARGAS, DÁMASO ÁNGEL;
ESQUIVEL GARCIA, JUAN RAMON;
MELA PRODOCIMO, MARITANA;
DE OLIVEIRA RIBEIRO, CIRO ALBERTO;
NETO, FRANCISCO FILIPAK;
CORDEIRO, ALESSANDRO LICK;
Cestari, M.M.;
DE SOUZA, AMANDA CÂMARA;
MARTINS, CESAR DE CASTRO;
DA SILVA, CLEBER PINTO;
DE CAMPOS, SANDRO XAVIER
Palavra-chave:
Genotoxicidade;
ensaio cometa
Áreas do conhecimento:
Ciências Biológicas; Genética; Genética Animal; Mutagênese Ambiental
resumo ...
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AZEVEDO, CAROLINA AMARAL BUENO;
DA CUNHA, REGIANE STAFIM;
JUNHO, CAROLINA VICTÓRIA CRUZ;
DA SILVA, JESSICA VERÔNICA;
MORENO-AMARAL, ANDRÉA N.;
DE MORAES, THYAGO PROENÇA;
CARNEIRO-RAMOS, MARCELA SORELLI;
Andréa Emília Marques Stinghen
Palavra-chave:
Uremic Toxins;
peritoneal dialysis;
extracellular vesicles
Áreas do conhecimento:
Ciências da Saúde; nephrology;
Ciências Biológicas; Bioquímica; Bioquímica
resumo ...
Cardiorenal syndrome (CRS) is described as primary dysfunction in the heart culminating in renal injury or vice versa. CRS can be classified into five groups, and uremic toxin (UT) accumulation is observed in all types of CRS. Protein-bound uremic toxin (PBUT) accumulation is responsible for permanent damage to the renal tissue, and mainly occurs in CRS types 3 and 4, thus compromising renal function directly leading to a reduction in the glomerular filtration rate (GFR) and/or subsequent proteinuria. With this decrease in GFR, patients may need renal replacement therapy (RRT), such as peritoneal dialysis (PD). PD is a high-quality and home-based dialysis therapy for patients with end-stage renal disease (ESRD) and is based on the semi-permeable characteristics of the peritoneum. These patients are exposed to factors which may cause several modifications on the peritoneal membrane. The presence of UT may harm the peritoneum membrane, which in turn can lead to the formation of extracellular vesicles (EVs). EVs are released by almost all cell types and contain lipids, nucleic acids, metabolites, membrane proteins, and cytosolic components from their cell origin. Our research group previously demonstrated that the EVs can be related to endothelial dysfunction and are formed when UTs are in contact with the endothelial monolayer. In this scenario, this review explores the mechanisms of EV formation in CRS, uremia, the peritoneum, and as potential biomarkers in peritoneal dialysis.
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Beatriz Zanutto Salviato;
Ana Maria Raymundi;
Thiago Rodrigues da Silva;
Bruna Salemme;
Jeferson Machado Batista;
Fabiano Soares Araújo;
GUIMARAES, FRANCISCO S.;
Leandro José Bertoglio;
Cristina Aparecida Jark Stern
Palavra-chave:
ansiedade;
canabidiol;
Delta - 9 tetrahidrocanabinol;
dopamina;
fêmeas;
PTSD
Áreas do conhecimento:
Ciências Biológicas; Farmacologia; Neuropsicofarmacologia
resumo ...
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TODO BOM, MARITZA ARAUJO;
BOTTON, VANDERLEIA;
ALTHEIA, FERNANDA MARCHESINI;
THOMAS, JULIANA CHRISTINA;
PIOVAN, LEANDRO;
CÓRDOVA, JESÚS;
MITCHELL, DAVID ALEXANDER;
KRIEGER, NADIA
Palavra-chave:
lipase;
enantiosseletividade;
sólido fermentado;
Rhizopus microsporus
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Biotecnologia;
Ciências Biológicas; Bioquímica; Enzimologia
resumo ...
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GOMES, LUCAS ROBERTO PEREIRA;
SOUZA, DIEGO DE SANTANA;
Cláudio J B Carvalho
Palavra-chave:
Phylogenetic analysis;
Divergence time;
Molecular analysis;
Calyptratae;
muscoidea;
Oestroidea
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes
resumo ...
Anthomyiidae is a family of flies distributed worldwide comprising approximately 2,000 species, which, based on molecular analyses, belong to the Muscoidea grade. The phylogenetic data for this fam...
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COSTA, J. C. R.;
MARCHI, G. H.;
SANTOS, C. S.;
ANDRADE, M. C. M.;
CHAVES JUNIOR, S. P.;
Mário Antonio NavarroSilva;
MELO, M. N.;
Andrey Jose de Andrade
Palavra-chave:
Diptera;
Psychodidae;
unidade de conservação
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Fisiologia dos Grupos Recentes
resumo ...
Genus and species of phlebotomine sand flies have been recorded and described in caves in Brazil, but no study has provided the food source used by sand flies in these environments. Herein, we identified the blood source used by sand fly species in caves located at “Quadrilátero Ferrífero” (QF), Minas Gerais state. Specimens were manually collected near or on anurans inside ferruginous caves in Serra do Gandarela National Park and Serra do Rola Moça State Park. Males and females were placed in vials with 70% alcohol and stored at −10°C. Females engorged, after specific identification, had DNA extracted and followed for PCR amplification using specific primers. Sequencing was analyzed in the GenBank and Barcode of Life. A total of 198 specimens were collected (107 females and 91 males), all of them belonging to species Sciopemyia aff. microps (88.89%), Sciopemyia sordellii (10.61%), or Martinsmyia oliveirai (0.50%). When it comes to the females, 89 were S. aff. microps and 18 S. sordellii. Nineteen engorged females of S. aff. microps were analyzed and most of them (n=18) presented blood from Bokermannohyla martinsi and one contained blood from Scinax fuscovarius. The blood present in engorged females of S. sordellii (n=4) was from B. martinsi. Sciopemyia genus specimens are commonly found in collections carried out inside natural caves, but this was the first study to prove that females of this genus feed on cold-blooded animals in nature. • Here we proved that sand flies feed in cold-blooded animals in in Brazilian caves. • Females of the Sciopemyia genus were for the first time found feeding in natural habitats. • Anurans of the family Hylidae were identified as source by molecular analyzes. • Insect bloodmeal identification can help assessing the fauna in several biomes. • This is the first record of S. aff. microps in caves of Brazil.
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BACCI, LUCAS F.;
Renato Goldenberg;
MICHELANGELI, FABIAN A.
resumo ...
Premise of research. We present here the first reports of vivipary in Neotropical Melastomataceae and remark on the evolutionary relationships among the three lineages that share this feature.Metho...
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BARAZETTI, JÉSSICA FERNANDA;
CARVALHO DE OLIVEIRA, JAQUELINE;
JUCOSKI, TAYANA SHULTZ;
CARVALHO, TAMYRES MINGORANCE;
VEIGA, RAFAELA NASSER;
KOHLER, ANA FLÁVIA;
BAIG, JUMANAH;
AL BIZRI, HEND;
Daniela Fiori Gradia;
MADER, SYLVIE
Palavra-chave:
Breast cancer;
estrogen receptor;
tamoxifen;
endocrine resistance;
ncRNAs;
lncRNA
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica
resumo ...
Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer mortality among women. Two thirds of patients are classified as hormone receptor positive, based on expression of estrogen receptor alpha (ERα), the main driver of breast cancer cell proliferation, and/or progesterone receptor, which is regulated by ERα. Despite presenting the best prognosis, these tumors can recur when patients acquire resistance to treatment by aromatase inhibitors or antiestrogen such as tamoxifen (Tam). The mechanisms that are involved in Tam resistance are complex and involve multiple signaling pathways. Recently, roles for microRNAs and lncRNAs in controlling ER expression and/or tamoxifen action have been described, but the underlying mechanisms are still little explored. In this review, we will discuss the current state of knowledge on the roles of microRNAs and lncRNAs in the main mechanisms of tamoxifen resistance in hormone receptor positive breast cancer. In the future, this knowledge can be used to identify patients at a greater risk of relapse due to the expression patterns of ncRNAs that impact response to Tam, in order to guide their treatment more efficiently and possibly to design therapeutic strategies to bypass mechanisms of resistance.
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