Publicações - ciências biológicas


CUENCA, ANDRÉ L.R.; Marta Marques de Souza; Carolina Arruda de Oliveira Freire
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY, v. 259, p. 111001 2021 DOI
Palavra-chave: osmoregulation; osmoconformador; decápodos; regulação de volume
Áreas do conhecimento: Ciências Biológicas; Fisiologia Comparada; Fisiologia Comparativa da Osmorregulação
resumo ...
Rafaela Nasser Veiga; Jaqueline Carvalho de Oliveira; Daniela Fiori Gradia
Journal of Molecular Medicine, v. 1, p. 1 2021 DOI
Palavra-chave: PBX1; cancer hallmarks; pioneer factor; Biomarkers
Áreas do conhecimento: Ciências Biológicas; Genética Humana e Médica; Ciências Biológicas; Genética; Biologia Molecular
resumo ...
Pre-B-cell leukemia homeobox transcription factor 1 (PBX1) was first identified as part of a fusion protein resulting from the chromosomal translocation t(1;19) in pre-B cell acute lymphoblastic leukemias. Since then, PBX1 has been associated with important developmental programs, and its expression dysregulation has been related to multifactorial disorders, including cancer. As PBX1 overexpression in many cancers is correlated to poor prognosis, we sought to understand how this transcription factor contributes to carcinogenesis, and to organize PBX1’s roles in the hallmarks of cancer. There is enough evidence to associate PBX1 with at least five hallmarks: sustaining proliferative signaling, activating invasion and metastasis, inducing angiogenesis, resisting cell death, and deregulating cellular energetics. The lack of studies investigating a possible role for PBX1 on the remaining hallmarks made it impossible to defend or refute its contribution on them. However, the functions of some of the PBX1’s transcription targets indicate a potential engagement of PBX1 in the avoidance of immune destruction and in the tumor-promoting inflammation hallmarks. Interestingly, PBX1 might be a player in tumor suppression by activating the transcription of some DNA damage response genes. This is the first review organizing PBX1 roles into the hallmarks of cancer. Thus, we encourage future studies to uncover the PBX1’s underlying mechanisms to promote carcinogenesis, for it is a promising diagnostic and prognostic biomarker, as well as a potential target in cancer treatment.
GUARNIZO, ANDRÉS FELIPE CAMARGO; WOICIECHOWSKI, ADENISE LORENCI; Miguel Noseda; TORRES, LUIS ALBERTO ZEVALLOS; FILHO, ARION ZANDONA; RAMOS, LUIZ PEREIRA; ALBERTO JUNIOR LETTI, LUIZ; Soccol, Carlos Ricardo
BIORESOURCE TECHNOLOGY, v. 320, p. 124212 2021 DOI Home page
Palavra-chave: yeast; polysaccharides; B-glucans; Pichia; oil palm; Pentose-rich hydrolysate
Áreas do conhecimento: Ciências Biológicas; Biotecnologia; Ciências Biológicas; Bioquímica; Carboidratos
resumo ...
Pentose-rich hydrolysate obtained from dilute acid pretreatment of oil palm empty fruit bunches was successfully consumed by pentose-consuming yeasts:…
Dominicky Cristina Serrano; Marcos Lúcio Corazza; MITCHELL, DAVID ALEXANDER; KRIEGER, NADIA
BIOTECHNOLOGY LETTERS, v. 43, p. 503-509, 2021 DOI
Palavra-chave: Fermentação em estado sólido; sólidos fermentados; CO2 Supercrítico; esterificação
Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Biotecnologia
resumo ...
Lipases are often used in immobilized form, but commercial immobilized lipases are costly. An alternative is to produce lipases in solid-state fermentation, dry the solids and then use the “dry fermented solids” (DFS) directly. We produced DFS by growing Burkholderia contaminans on a mixture of sugarcane bagasse and sunflower seed meal and used the DFS to esterify oleic acid with ethanol in subcritical and supercritical CO2 at 40 °C. Compared to a control without CO2 at atmospheric pressure, subcritical CO2 at 30 bar improved esterification activity 1.2-fold. Higher pressures, including supercritical pressures up to 150 bar, reduced activity to less than 80% of the control. At 30 bar, the esterification activity was improved a further 1.8-fold with the addition of 9% water (i.e. 9 g water per 100 g oleic acid) to the reaction medium. A subcritical CO2 atmosphere, with the addition of a small amount of water, improved the esterification activity of DFS containing lipases of Burkholderia contaminans.
VERSIANE, ANA FLÁVIA ALVES; ROMERO, ROSANA; REGINATO, MARCELO; WELKER, CASSIANO A DORNELES; MICHELANGELI, FABIÁN A; Renato Goldenberg
BOTANICAL JOURNAL OF THE LINNEAN SOCIETY, v. 197, n. 1, p. 35-60, 2021 DOI
Áreas do conhecimento: Ciências Biológicas; Taxonomia Vegetal; Taxonomia de Fanerógamos
resumo ...
Abstract. Microlicieae are a monophyletic tribe comprising seven genera: Chaetostoma, Lavoisiera, Microlicia s.s., Poteranthera, Rhynchanthera, Stenodon and Tre
MEYER, FABRÍCIO SCHMITZ; REGINATO, MARCELO; SMIDT, ERIC CAMARGO; DE SANTIAGO GÓMEZ, JESÚS RICARDO; MICHELANGELI, FABIÁN A; Renato Goldenberg
BOTANICAL JOURNAL OF THE LINNEAN SOCIETY, v. 197, p. 170-189, 2021 DOI
Áreas do conhecimento: Ciências Biológicas; Taxonomia Vegetal; Taxonomia de Fanerógamos
resumo ...
Abstract. In the past decade, several phylogenetic studies based on molecular data have been generated and changed our view on the evolutionary history and clas
VASCONCELOS, ANA C O; WENDT, LISIANE D; Cláudio J B Carvalho
Austral Entomology, v. 60, p. 330-350, 2021 DOI
Palavra-chave: Taxonomy
Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia; Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes
resumo ...
VASCONCELOS, ANA C O; WENDT, LISIANE D; Cláudio J B Carvalho
Austral Entomology, v. 60, p. aen.12534 2021 DOI
Palavra-chave: Maximum parsimony; morphology; Neotropical; Phylogeny; Sexual dimorphism; Tephritoidea
Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia; Ciências Biológicas; Morfologia; Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes
resumo ...
Pterocallini is one of the largest tribes within Ulidiidae, with more than 130 species described in 27 genera. The great majority of Pterocallini species are endemic to the Neotropics. They are chara...
Romain Nattier; Alice Michel-Salzat; Almeida, LM.; Pascaline Chifflet-Belle; Alexandra Magro; Karen Salazar; Gael J. Kergoat
SYSTEMATIC ENTOMOLOGY, v. 12480, p. 1-17, 2021 DOI
Palavra-chave: Phylogeny; Molecular data; Coccinellidae
Áreas do conhecimento: Ciências Biológicas; Entomologia; Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes
resumo ...
MAZEPA, ESTER; MOGOR, ÁTILA F.; Miguel Noseda; MALBURG, BARBARA V.; MÓGOR, GILDA; DE OLIVEIRA, AMANDA C.; AMATUSSI, JULIANA O.; CORRÊA, DIEGO O.; LEMOS, JACQUELINE S.; Diogo R. B. Ducatti; Duarte, Maria Eugênia R.
Algal Research-Biomass Biofuels and Bioproducts, v. 59, p. 102434 2021 DOI
Palavra-chave: microalgas; Atividade bioestimulante vegetal; Fitohormônios; glicosídeos; estrutura química; Chlorophyta
Áreas do conhecimento: Ciências Biológicas; Biotecnologia; Ciências Biológicas; Bioquímica; Química de Macromoléculas; Glicídeos
resumo ...
Total de registros: