Publicações - ciências biológicas
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Kamila Alcala Gonçalves;
Thierry Grima de Cristo;
Flavia Moreira da Fonseca;
Rosangela Locatelli Dittrich;
Renato Silva de Sousa;
Mary Suzan Varaschin;
Ana Paula Brenner Bush;
Alda Lúcia Gomes Monteiro;
Marília Koch;
Rafael Carneiro Costa;
LASKOSKI, LUCIANE M.;
Claudia Martins Galindo
VETERINARY PARASITOLOGY: REGIONAL STUDIES AND REPORTS,
v. 23,
p. 1-5,
2021
Palavra-chave:
Neosporose;
ovinos;
lambs
Áreas do conhecimento:
Ciências Biológicas; Medicina Veterinária
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FERNANDEZ-HILARIO, ROBIN;
Renato Goldenberg;
Fabián A. Michelangeli
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Renato Goldenberg;
Lucas de Freitas Bacci;
Thuane Bochorny;
Marcelo Reginato
Áreas do conhecimento:
Ciências Biológicas; Taxonomia Vegetal; Taxonomia de Fanerógamos
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DE BARROS, RODOLFO CORRÊA;
Rosana Moreira da Rocha
Palavra-chave:
ASCIDIACEA;
Styelidae;
Styela;
Taxonomia;
Biodiversidade
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes;
Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes; Taxonomia de Ascidiacea
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(en)
Two new species of the genus Styela are described, with very rare characteristics in this genus: both are shallow-water and tropical, with more than two gonads in each side of the body. Styela panamensis sp. nov. is described from specimens collected in Bocas del Toro, Atlantic coast of Panama, and Styela multicarpa sp. nov. from specimens collected in Espírito Santo, Brazil and Margarita Island, Venezuela. They are probably native to the south Caribbean and S. multicarpa sp. nov. is introduced in Brazil.
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PAULERT, ROBERTA;
MARIOTTI, LORENZO;
PISTELLI, LAURA;
ASCRIZZI, ROBERTA;
MALATESTA, SILVIA;
BERNI, PAOLO;
Miguel Noseda;
MAZETTO DE CARVALHO, MARIANA;
MARCHIONI, ILARIA;
PISTELLI, LUISA;
RABELLO DUARTE, MARIA EUGÊNIA
Palavra-chave:
ulvan;
Sulfated Polysaccharide;
Bioestimulante vegetal;
Biofertilizante;
Ulva intestinalis;
Fitohormônios
Áreas do conhecimento:
Ciências Biológicas; Biotecnologia
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Natural elicitors from macroalgae may affect plant secondary metabolites. Ulvan is a sulfated heteropolysaccharide extracted from green seaweed, acting as both a plant biotic protecting agent, and a plant elicitor, leading to the synthesis of signal molecules. In this work, the aqueous extract of Ulva intestinalis L., mainly composed of ulvan, was used as foliar-spraying treatment and its eliciting effect was investigated in basil (Ocimum basilicum L.) and parsley (Petroselinum crispum L.). Antioxidant metabolites (polyphenols and carotenoids), volatile compounds (both in headspace emissions and hydrodistilled essential oils), and hormones (jasmonic acid, salicylic acid, salicylic acid 2-O-β-D-glucoside, abscisic acid, and azelaic acid) were quantified. The foliar-spraying treatment with U. intestinalis extract increased salicylic acid and its β-glucoside in parsley; in basil, it induced the accumulation of jasmonic and abscisic acids, indicating the presence of a priming effect. In basil, the elicitation caused a change of the essential oil (EO) chemotype from methyl eugenol/eugenol to epi-α-cadinol and increased sesquiterpenes. In parsley EO it caused a significant accumulation of 1,3,8-p-menthatriene, responsible of the typical “parsley-like” smell. In both species, the phenylpropanoids decreased in headspace and EO compositions, while the salicylic acid concentration increased; this could indicate a primarily defensive response to U. intestinalis extract. Due to the evidenced significant biological activity, U. intestinalis extract used as an elicitor may represent a suitable tool to obtain higher amounts of metabolites for optimizing plant flavor metabolites.
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MATHIAS, CAROLINA;
MUZZI, JOÃO CARLOS DEGRAF;
ANTUNES, BRUNA BORBA;
Daniela Fiori Gradia;
CASTRO, MAURO A. A.;
CARVALHO DE OLIVEIRA, JAQUELINE
Palavra-chave:
lncRNA;
Breast cancer
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Biologia Geral; Bioinformática
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Breast cancer (BRCA) is the most leading cause of cancer worldwide. It is a heterogeneous disease with at least five molecular subtypes including luminal A, luminal B, basal-like, HER2-enriched, and normal-like. These five molecular subtypes are usually stratified according to their mRNA profile patterns; however, ncRNAs are increasingly being used for this purpose. Among the ncRNAs class, the long non-coding RNAs (lncRNAs) are molecules with more than 200 nucleotides with versatile regulatory roles; and high tissue-specific expression profiles. The heterogeneity of BRCA can also be reflected regarding tumor microenvironment immune cells composition, which can directly impact a patient’s prognosis and therapy response. Using BRCA immunogenomics data from a previous study, we propose here a bioinformatics approach to include lncRNAs complexity in BRCA molecular and immune subtype. RNA-seq data from The Cancer Genome Atlas (TCGA) BRCA cohort was analyzed, and signal-to-noise ratio metrics were applied to create these subtype-specific signatures. Five immune-related signatures were generated with approximately ten specific lncRNAs, which were then functionally analyzed using GSEA enrichment and survival analysis. We highlighted here some lncRNAs in each subtype. LINC01871 is related to immune response activation and favorable overall survival in basal-like samples; EBLN3P is related to immune response suppression and progression in luminal B, MEG3, XXYLT1-AS2, and LINC02613 w...
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Augusto, Danillo G.;
WITTIG, MICHAEL;
FRANKE, ANDRE;
BUSCH, HAUKE;
SCHMIDT, ENNO;
ROSELINO, ANA MARIA;
TARAZONA-SANTOS, EDUARDO;
BOLDT, ANGELICA B.W.;
Maria Luiza Petzl-Erler;
DE ALMEIDA, RODRIGO C.;
FARIAS, TICIANA D.J.;
MAGALHÃES, WAGNER C.S.;
Danielle Malheiros Ferreira;
LIMA-COSTA, MARIA FERNANDA;
BARRETO, MAURÍCIO L.;
HORTA, BERNARDO L.;
Kumar, Vinod
Palavra-chave:
Pemphigus;
GWAS;
pemphigus foliaceus;
NOTCH4;
STEAP2-AS1;
genome wide association study
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Imunologia; Imunogenética;
Ciências Biológicas; Bioquímica; Biologia Molecular
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danillo gardenal augusto;
Vinod Kumar;
Michael Wittig;
Andre Franke;
Hauke Busch;
Enno Schmidt;
Ana Maria F. Roselino;
Eduardo Tarazona-Santos;
Angelica Beate Winter Boldt;
Maria Luiza Petzl-Erler;
Rodrigo Coutinho de Almeida;
Ticiana D. J. Farias;
Wagner C. S. Magalhães;
Danielle Malheiros;
Maria Fernanda Lima-Costa;
Maurício L. Barreto;
Bernardo L. Horta;
Bahram Sanjabi
Palavra-chave:
pênfigo foliáceo;
GWAS;
polimorfismo;
NOTCH4;
STEAP2-AS1;
HLA
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética
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FAVRETTO, GIANE;
Andréa Emília Marques Stinghen;
DA CUNHA, REGIANE STAFIM;
FLORES SANTOS, ANDRESSA;
LEITOLIS, AMANDA;
SCHIEFER, ELBERTH MANFRON;
GREGÓRIO, PAULO CÉZAR;
FRANCO, CELIA REGINA CAVICHIOLO;
MASSY, ZIAD;
Dalboni, Maria Aparecida
Palavra-chave:
Uremic Toxins;
Endothelial dysfunction;
chronic kidney disease
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências da Saúde; Medicina; Nefrologia Experimental;
Ciências Biológicas; Biologia Geral; Biologia Celular
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DE ALBUQUERQUE, FELÍCIA PEREIRA;
DE OLIVEIRA, JHONES LUIZ;
DOS SANTOS MACHADO, LEILA;
RICHARDI, VINICIUS S.;
Mário Antonio NavarroSilva;
POMPÊO, MARCELO LUIZ MARTINS;
FRACETO, LEONARDO FERNANDES;
CARLOS, VIVIANE MOSCHINI
Palavra-chave:
Diptera;
Chironomidae;
Chironomus sancticaroli;
ecotoxicologia
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Fisiologia dos Grupos Recentes
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Atrazine was banned by the European Union in 2004, but is still used in many countries. Agricultural research employing nanotechnology has been developed in order to reduce the impacts to the environment and nontarget organisms. Nanoatrazine was developed as a carrier system and have been considered efficient in weed control. However, its toxicity must be verified with nontarget organisms. In this context, the aim of the present study was to investigate ecotoxicological effects of solid lipid nanoparticles (empty and loaded with atrazine) and atrazine on Chironomus sancticaroli larvae, evaluating the endpoints: mortality, mentum deformity, development rate and biochemical biomarkers. The contaminant concentrations used were 2, 470, 950, and 1900 μg L−1 in acute (96 h) and 2 μg L−1 in subchronic (10 days) bioassays. An environmentally relevant concentration of atrazine (2 μg L−1) presented toxic and lethal effects towards the larvae. The nanoparticles loaded with atrazine showed toxic effects similar to free atrazine, causing mortality and biochemical alterations on the larvae. The nanoparticle without atrazine caused biochemical alterations and mortality, indicating a possible toxic effect of the formulation on the larvae. In the acute bioassay, most concentrations of nanoparticles loaded with atrazine were not dose dependent for the endpoint mortality. Only the atrazine concentration of 470 μg L−1 was statistically significant to endpoint mentum deformity. The atrazine and nanoparticles (with and without atrazine) did not affect larval development. The results indicate that Chironomus sancticaroli was sensitive to monitor nanoatrazine, presenting potential to be used in studies of toxicity of nanopesticides.
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