Publicações - ciências da saúde
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CANCELLO, LAURA L.;
CEOLIN, GILCIANE;
Adriano Marçal Pimenta;
BRESSAN, JOSEFINA;
HERMSDORFF, HELEN H.M.;
STEEMBURGO, THAIS
Palavra-chave:
NOVA classification;
Food consumption;
Type 2 diabetes
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DA SILVA, FERNANDA MARIA OLIVEIRA;
Adriano Marçal Pimenta;
JUVANHOL, LEIDJAIRA LOPES;
HERMSDORFF, HELEN HERMANA MIRANDA;
BRESSAN, JOSEFINA
Palavra-chave:
Hypertension;
Food consumption;
Branched-chain amino acids
Áreas do conhecimento:
Ciências da Saúde; Enfermagem; Análise Nutricional de População;
Ciências da Saúde; Enfermagem; Epidemiologia;
Ciências da Saúde; Saúde Coletiva
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Recent studies show that dietary intake of branched-chain amino acids (BCAA) may be associated with chronic diseases, including hypertension. This study aimed to evaluate the association between BCAA intake and the incidence of hypertension. This longitudinal study included 3192 participants (M = 1067, F = 2125; mean age = 34 years) from the Cohort of Universities of Minas Gerais (CUME Study, 2016–2022), Brazil. BCAA intake was assessed using a validated 144-item semi-quantitative food frequency questionnaire. Participants were classified as an incident case of hypertension when they were free of this disease at baseline and had systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg, or used antihypertensives or received a diagnosis of hypertension by a physician in at least one follow-up. Crude and adjusted Cox regression models were used to evaluate the association between BCAA intake and incidence of hypertension. After a median follow-up time of 2.21 years, 213 new cases of hypertension were identified. A direct association was shown between the second tertile of total BCAA (HR = 1.76; 95% CI 1.06–2.90) and isoleucine (HR = 2.04; 95% CI 1.14–3.62) consumption and the incidence of hypertension in males. A direct association was observed between the second tertile of valine (HR = 1.74; 95% CI 1.01–3.02) and leucine (HR = 1.94; 95% CI 1.10–3.41) intake and hypertension incidence among adults aged 30–39 years. Conversely, among younger participants (18–29 years), leucine intake in the second tertile was inversely associated with hypertension (HR = 0.36; 95% CI 0.14–0.89). The main foods that contributed to BCAA intake were unprocessed chicken (16.56%), dairy (16.33%), unprocessed beef (14.98%), fish (7.85%), and beans/lentils (6.44%). Our findings may provide valuable evidence to support dietary interventions for the primary prevention of hypertension.
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Francisco Jose de Menezes Junior;
Neiva Leite;
Caroline Brand;
Maiara Cristina Tadiotto;
Patrícia Ribeiro Paes Corazza;
Tatiana Aparecida Affornali Tozo;
Kátia Sheylla Malta Purim;
Jorge Mota;
Beatriz Oliveira Pereira;
Rafaela Rosário
Palavra-chave:
adolescents;
Physical Exercise;
Therapeutics
Áreas do conhecimento:
Ciências da Saúde; Educação Física; História do Esporte
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The effects of different exercise intensities on cognitive outcomes and brain-derived neurotrophic factor (BDNF) concentrations in adolescents with overweight/obesity are not yet fully elucidated. This study aimed: (a) to compare the prevalence of responders to cognitive function and BDNF concentration in adolescents with overweight/obesity participating in a 12-week intervention with high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT), and (b) to analyze whether cardiorespiratory fitness (CRF) can explain differences in inter-individual variability between responders and non-responders. Adolescents with overweight/obesity were assigned to HIIT (n = 15), MICT (n = 14), or CG (n = 24). Anthropometrics, body composition, CRF, basal BDNF, and cognitive performance (Trial Making Test (TMT) and Stroop Test (ST)) were evaluated pre- and post-intervention. Training was performed on stationary bikes (3×/week for 12 weeks). The prevalence of responders in ST and TMT was higher in the HIIT group than in CG (93–62%, p = 0.029; 67–33%, p = 0.043), with no differences in MICT. No group differences were found for BDNF responders (HIIT:73%-MICT:71%-CG:46%, p = 0.263). ST and TMT responders had greater CRF improvements than non-responders. HIIT elicited a higher prevalence of cognitive responders than CG. CRF improvements may partially explain individual variability in responsiveness to cognitive outcomes.
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LEMOS, MARIA JULIA;
QUEIROZ, LAURA FONSECA;
DINIZ, ALICE FRANÇA;
LONGO DA SILVA, CELENE MARIA;
DOS SANTOS, PRISCILA LUIZA;
DE OLIVEIRA GOMIDE, PATRÍCIA;
FERRAZ, JACQUELINE M.;
Andrea Mora De Marco Novellino
Palavra-chave:
Menopause;
vulvovaginal atrophy;
DHEA;
prasterone;
Intrarosa;
Dehydroepiandrosterone
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ic postmenopausal women.
Objective:
To assess the therapeutic efficacy of intravaginal dehydroepiandrosterone (DHEA) for vulvovaginal atrophy in postmenopausal women.
Evidence review:
A systematic literature search was performed in PubMed, Embase, and the Cochrane Library for studies published up to July 2025. Search terms included “DHEA,” “prasterone,” “Intrarosa,” and “dehydroepiandrosterone.” Randomized controlled trials (RCTs) evaluating intravaginal DHEA in postmenopausal women were included. Data extraction followed predefined inclusion and exclusion criteria. Risk of bias was assessed, and pooled analyses were conducted using random-effects models.
Findings:
Six RCTs representing five unique RCTs (n=1,611) involving postmenopausal women with VVA were included. Compared with placebo, intravaginal DHEA demonstrated significant improvements in two primary outcomes: vaginal dryness with a mean difference of −0.23 (95% CI, −0.35 to −0.11) and dyspareunia of −0.40 (95% CI: −0.66 to −0.15). No major safety concerns were reported, and adverse effects were mild and infrequent. The evidence consistently supported both statistical and clinical benefits of DHEA across trials, with low to moderate heterogeneity.
Conclusions and relevance:
Intravaginal DHEA significantly improves vulvovaginal symptoms, particularly vaginal dryness and dyspareunia, in postmenopausal women. These findings underscore its role as an effective and well-tolerated therapeutic option for the management of genitourinary syndrome of menopause, with potential to enhance quality of life....
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Angela Caroline Giacomitti Cardoso;
Maria Thereza Oliveira Souza;
André Mendes Capraro
Palavra-chave:
Bodybuilding;
women's sports;
Oral History;
muscular body;
body history
Áreas do conhecimento:
Ciências da Saúde; Educação Física; História do Esporte
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Evanise Angela Alves Bolak;
Maiara Cristina Tadiotto;
Diogo Homann;
Caroline Brand;
Marcia R Messaggi Gomes Dias;
Beatriz Oliveira Pereira;
Rafaela Rosário;
Neiva Leite
RETOS,
v. 78,
p. 806-819,
2026
Palavra-chave:
CHILDHOOD;
Health;
Hypertension;
Physical Activity;
Schoolchildren
Áreas do conhecimento:
Ciências da Saúde; Educação Física; História do Esporte;
Ciências da Saúde; Enfermagem;
Ciências da Saúde; Medicina; Clínica Médica; Pediatria
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Núbia Isabela Macedo Martins;
Rodrigo Oliveira Mazza;
Ana Elisa Lemos Silva;
Daniel Weintraub;
Vera Lúcia Santos de Britto;
Cynton Lourenço Corrêa
Journal of Geriatric Psychiatry and Neurology,
v. 00,
p. 1-11,
2026
Palavra-chave:
atividades de vida diária;
cognição;
Doença de Parkinson;
estudos de validação
Áreas do conhecimento:
Ciências da Saúde; Fisioterapia e Terapia Ocupacional; Fisioterapia neurofuncional
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Maiara Cristina Tadiotto;
Neiva Leite;
Caroline Brand;
Ana Duarte;
Claudia Augusto;
Maria José Silva;
Jorge Mota;
Beatriz Oliveira Pereira;
Rafaela Rosário
Palavra-chave:
Adiposity;
Children;
blood pressure;
Hypertension;
Physical Activity
Áreas do conhecimento:
Ciências da Saúde; Educação Física; História do Esporte;
Ciências da Saúde; Enfermagem; Enfermagem em Saúde da Criança e do Adolescente; Assistência de Enfermagem
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Obesity is associated with comorbidities, including hypertension, which have been diagnosed in the pediatric population. The aim of this study was to verify the mediator role of physical activity in the relationship between anthropometric indicators and blood pressure (BP) in children with normal weight and children with overweight/obesity. The BeE-school project included 728 Portuguese children (376 boys, 352 girls), aged 6 to 10 years old, who were divided into two groups: children with normal weight and children with overweight/obesity, according to body mass index z-score (BMI-z). Body mass, height, waist circumference (WC), systolic BP (SBP) and diastolic BP (DBP) were assessed. Tri-ponderal mass index (TMI), waist-to-height ratio (WHtR) and mean BP (MBP) were calculated. Sedentary behavior and moderate-to-vigorous physical activity (MVPA) were determined by accelerometry. Mediation analyses were conducted considering predictors (WC, WHtR, TMI), mediators (MVPA on weekdays, weekend, total), outcomes (SBP, DBP, MBP). Children with overweight/obesity had higher mean values for BP measurements compared to their normal weight peers. In the correlations were not observed associations between anthropometric indicators and BP variables in children with normal weight, but MVPA on weekdays and MVPA total showed positive associations with SBP. However, children with overweight/obesity presented significant positive associations between all anthropometric indicators and BP variables. The present study provides evidence that physical activity functions as a competitive mediator in relationship between TMI and BP in children with overweight/obesity. The overweight simultaneously elevates BP directly while reducing protective physical activity engagement in Portuguese children.
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DE MENEZES-JUNIOR, FRANCISCO JOSÉ;
BRAND, CAROLINE;
TADIOTTO, MAIARA CRISTINA;
CORAZZA, PATRICIA RIBEIRO PAES;
TOZO, TATIANA APARECIDA AFFORNALI;
Kátia Sheylla Malta Purim;
CRISTI-MONTERO, CARLOS;
Neiva Leite
Palavra-chave:
adolescence;
Aerobic training;
CARDIORESPIRATORY FITNESS;
executive function;
Handgrip Strength
Áreas do conhecimento:
Ciências da Saúde; Educação Física; História do Esporte
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MORAES-SANTOS, JOÃO VITOR;
BRESSAN, JOSEFINA;
Adriano Marçal Pimenta;
HERMSDORFF, HELEN HERMANA MIRANDA;
GRILI, PATRÍCIA PAULA DA FONSECA;
GUANDALINI, VALDETE REGINA;
VIDIGAL, FERNANDA DE CARVALHO;
MARQUES-ROCHA, JOSÉ LUIZ
Palavra-chave:
Eating behavior;
depressive disorder;
Nutrition therapy;
Nutritional epidemiology;
Factor Analysis
Áreas do conhecimento:
Ciências da Saúde; Enfermagem; Análise Nutricional de População;
Ciências da Saúde; Enfermagem; Epidemiologia;
Ciências da Saúde; Saúde Coletiva
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