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Publicações - ciências biológicas

Genetic screening for transthyretin familial amyloid polyneuropathy to avoid misdiagnosis in patients with polyneuropathy associated with high protein in the cerebrospinal fluid Paulo José Lorenzoni; GIUGNO, VINICIUS RIEGEL; DUCCI, RENATA DAL-PRÁ; Lineu Cesar Werneck; CLAUDIA S K KAY; Scola, Rosana Herminia ACTA NEUROLOGICA BELGICA, v. 123, n. 4, p. 1655-1657, 2023 DOI Palavra-chave: Neuropatia amiloide; Polineuropatias Áreas do conhecimento: Ciências Biológicas; Genética Humana e Médica; Neurologia resumo ...
Germination and Post-Seminal Development of Mimosa L. (Fabaceae) in Diesel Oil-Contaminated Soil Renata Charvet Inckot; Gedir de Oliveira Santos; Cleusa Bona; Luiz Antônio de Souza BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, v. 110, n. 1, p. 18 2023 DOI Palavra-chave: Anatomia de Leguminosa; polição por hidrocarbonetos; Anatomia vegetal; Mimosaceae Áreas do conhecimento: Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia; Ciências Biológicas; Botânica; Morfologia Vegetal; Ciências Biológicas; Botânica; Fisiologia Vegetal resumo ... Germination and post-seminal development are important stages for the establishment of plants and for determining their tolerance to diesel oil. Diesel-tolerant species can contribute to the recovery of contaminated areas, and leguminous plants are promising in the treatment of contaminated soil through nitrogen fixation. This study identified the effects of diesel oil-contaminated soil on the germination and seedlings of the leguminous species Mimosa bimucronata, M. flocculosa, and M. scabrella var. aspericarpa. The experiment comprised two treatments contaminated (4% concentration) and uncontaminated soil and was performed in a greenhouse for 90 days, with evaluations 30, 60, and 90 days after sowing. Germination was not affected, but most root and aerial system parameters were statistically lower in contaminated soil, indicating low initial development potential in soil contaminated with diesel oil. Moreover, the negative effects increased with higher exposure time to the contaminant.
Glucocorticoid Receptor Gene (NR3C1) Polymorphisms and Metabolic Syndrome: Insights from the Mennonite Population KOLB, KATHLEEN LIEDTKE; HUNDT, JENNIFER ELISABETH; SHULDINER, ALAN R.; LOPES, FABIANA LEÃO; BOYSEN, TEIDE-JENS; FRANKE, ANDRE; PINTO, LUIS FELIPE RIBEIRO; SOARES-LIMA, SHEILA COELHO; KRETZSCHMAR, GABRIELA CANALLI; Angelica Beate Winter Boldt; MIRA, ANA LUIZA SPROTTE; AUER, EDUARDO DELABIO; BUCCO, ISABELA DALL?OGLIO; DE LIMA E SILVA, CARLA EDUARDA; DOS SANTOS, PRISCILA IANZEN; HOCH, VALÉRIA BUMILLER-BINI; OLIVEIRA, LUANA CAROLINE; HAUSER, ALINE BORSATO Genes, v. 14, n. 9, p. 1805 2023 DOI Palavra-chave: glucocorticoide; GR; eixo HPA; síndrome metabólica; menonita; metilação do DNA Áreas do conhecimento: Ciências Biológicas; Genética Humana e Médica resumo ... The regulation of the hypothalamic-pituitary-adrenal (HPA) axis is associated with polymorphisms and the methylation degree of the glucocorticoid receptor gene (NR3C1) and is potentially involved in the development of metabolic syndrome (MetS). In order to evaluate the association between MetS with the polymorphisms, methylation, and gene expression of the NR3C1 in the genetically isolated Brazilian Mennonite population, we genotyped 20 NR3C1 polymorphisms in 74 affected (MetS) and 138 unaffected individuals without affected first-degree relatives (Co), using exome sequencing, as well as five variants from non-exonic regions, in 70 MetS and 166 Co, using mass spectrometry. The methylation levels of 11 1F CpG sites were quantified using pyrosequencing (66 MetS and 141 Co), and the NR3C1 expression was evaluated via RT-qPCR (14 MetS and 25 Co). Age, physical activity, and family environment during childhood were associated with MetS. Susceptibility to MetS, independent of these factors, was associated with homozygosity for rs10482605C (OR = 4.74, pcorr = 0.024) and the haplotype containing TTCGTTGATT (rs3806855T_ rs3806854T_rs10482605C_rs10482614G_rs6188T_rs258813T_rs33944801G_rs34176759A_rs17209258T_rs6196T, OR = 4.74, pcorr = 0.048), as well as for the CCT haplotype (rs41423247C_ rs6877893C_rs258763T), OR = 6.02, pcorr = 0.030), but not to the differences in methylation or gene expression. Thus, NR3C1 polymorphisms seem to modulate the susceptibility to MetS in Mennonites, independently of lifestyle and early childhood events, and their role seems to be unrelated to DNA methylation and gene expression.
Guavira Fruit Pomace Promotes Immunomodulation and Reduction of Tumor Growth in Walker 256 Tumor-Bearing Rats Natalia Eirão Zulin; Bonatto S J; Luis Cláudio Fernandes; Lucimara Mach Côrtes Cordeiro; Iagher, Fabíola; Carolina Garcia Martins; Marcia Helena Appel; Débora Salles da Silva Coutinho; Amanda Plaça Bialli; Daiana M Bronoski; Stephanie Runianne Silva Carvalhal; Elisvânia Freitas dos Santos; Paulo Sérgio Loubert Filho CURRENT NUTRITION AND FOOD SCIENCE, v. 19, p. 1-10, 2023 DOI Home page Palavra-chave: cancer; Immune System; pectin Áreas do conhecimento: Ciências Biológicas; Fisiologia; Fisiologia de Órgãos e Sistemas; Fisiologia Endócrina resumo ...
Guiana dolphins use mangrove margins as a natural barrier to chase fish prey PIERRY, JULIA C.; MORETE, MARIA E.; Emygdio Leite de Araújo Monteiro-Filho; TEIXEIRA, CLARISSA R. ETHOLOGY, v. 00, p. 1-6, 2023 DOI Palavra-chave: Barrier feeding; Behavioral plasticity; Foraging tactics; Sotalia guianensis Áreas do conhecimento: Ciências Biológicas; Zoologia; Comportamento Animal resumo ...
Habitat use of Guiana dolphin Sotalia guianensis in a heavily urbanized embayment MEIRELLES, ACO; CHOI-LIMA, KF; CAMPOS, TM; Emygdio Leite de Araújo Monteiro-Filho; LOTUFO, TMC MARINE ECOLOGY PROGRESS SERIES, v. 722, p. 195-206, 2023 DOI Palavra-chave: Species distribution modelling; Generalized additive models; Habitat preference; Breakwaters; Barrier-feeding; Feeding strategy Áreas do conhecimento: Ciências Biológicas; Zoologia; Comportamento Animal; Ciências Biológicas; Zoologia; Zoologia; Ciências Biológicas; Ecologia; Ecologia Aplicada resumo ...
High hydrolytic activity of the metagenomic lipase LipC12 in deep eutectic solvents SOARES, GLÊYDISON AMARANTE; ALNOCH, ROBSON CARLOS; ALVES DOS SANTOS, LEANDRO; MAFRA, MARCOS ROGÉRIO; MITCHELL, DAVID ALEXANDER; KRIEGER, NADIA JOURNAL OF MOLECULAR LIQUIDS, v. 391, p. 123383 2023 DOI Palavra-chave: solventes eutéticos profundos; lipases; metagenômica; LipC12 Áreas do conhecimento: Ciências Biológicas; Bioquímica; Bioquímica dos Microorganismos; Biotecnologia resumo ...
How Can Different Land Uses Impact Aquatic Organisms? An Evaluation of Metabolic Alterations During Embryonic Development of Freshwater Fish, Rhamdia quelen PIFFERO, CAMILA; Silvia Romão; CAZAROLLI, LUISA; NASCIMENTO, CRISTIAN; SOBJAK, THAÍS; Donatti, Lucélia; DMENGEON, MARIA; GUIMARÃES, ANA ECOTOXICOLOGY AND ENVIRONMENTAL CONTAMINATION, v. 17, n. 2, p. 99-114, 2023 DOI Palavra-chave: Rhamdia quelen; fish Áreas do conhecimento: Ciências Biológicas; Ecologia; Ecologia de Ecossistemas resumo ...
How can the copepod (Thiébaud, 1912) be used to control mosquito production effectively in pots, plates, and slabs? LIMA-KEPPE, ISABELA; SAITO, VICTOR SATORU; SOARES, JAQUELINE FERNANDA; NUNES-SILVA, ALINE; Antonio Ostrensky Neto; FERREIRA, IURI EMMANUEL DE PAULA; PERBICHE-NEVES, GILMAR JOURNAL OF TROPICAL ECOLOGY, v. 39, p. e14 2023 DOI Home page Palavra-chave: zooplâncton; ecologia aquática; Controle de larvas Áreas do conhecimento: Ciências Biológicas; Ecologia; Ecologia Aplicada; Engenharias; Engenharia Mecânica; Engenharia Térmica; Controle Ambiental; Ciências Biológicas; Zoologia; Zoologia Aplicada; Controle Populacional de Animais resumo ... How can the copepod Mesocyclops longisetus (Thiébaud, 1912) be used to control mosquito production effectively in pots, plates, and slabs? - Volume 39
Identification, Antioxidant Capacity, and Matrix Metallopeptidase 9 (MMP-9) In Silico Inhibition of Haloarchaeal Carotenoids from Natronococcus sp. and Halorubrum tebenquichense DELGADO-GARCÍA, MARIANA; GÓMEZ-SECUNDINO, OSVALDO; RODRIGUEZ, JORGE A.; MATEOS-DÍAZ, JUAN CARLOS; Marcelo Muller dos Santos; AGUILAR, CRISTOBAL N.; CAMACHO-RUIZ, ROSA MARÍA Microorganisms, v. 11, n. 9, p. 2344 2023 DOI Palavra-chave: antioxidant; bacterioruberin; docking; haloarchaea Áreas do conhecimento: Ciências Biológicas; Bioquímica; Bioquímica dos Microorganismos resumo ...

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