Publicações - ciências biológicas
|
ROMA, LUCAS PARADIZO;
Regina Yoshie Hirai;
Jefferson Prado;
SANTOS, DÉBORAH YARA A. C.
Palavra-chave:
Abaxial wax;
Adaxial wax;
Cuticle;
Intracuticular wax;
Gleicheniales
Áreas do conhecimento:
Ciências Biológicas; Bioquímica; Bioquímica
resumo ...
|
|
BARACHO, DOUGLAS HENRIQUE;
Ana Teresa Lombardi
Palavra-chave:
Bioquímica;
Cianobactérias
resumo ...
Cyanobacteria are prokaryotic organisms with wide morphological and metabolic diversity. By means of photosynthesis, they convert inorganic compounds into biomolecules, which may have commercial interest. In this work, we evaluated 20 cyanobacterial strains regarding their physiological aspects such as growth, photosynthesis and biochemical composition, some of which are revealed here for the first time. The organisms were cultivated in cylindrical photobioreactors (CPBR) for 144 h and the biomass was obtained. The light inside cultures was constant throughout experimental time and maintained at the saturation irradiance (Ik) of each species. Culture pH was maintained within 7.8 and 8.4 by automatic CO2 bubbling. Growth rate, dry biomass, chlorophyll a, carotenoids, phycocyanin, proteins, carbohydrates, lipids, polyhydroxyalkanoate (PHA) and antioxidant activity were determined. The proportionality of the biochemical composition varied among species, as well as the growth rates. Leptolyngbya sp. and Nostoc sp. (CCIBt3249) showed growth rates in the range of 0.7–0.8 d−1, followed by Rhabdorderma sp. (~ 0.6 d−1), and Phormidium sp. (~ 0.5 d−1). High carotenoid content was obtained in Rhabdoderma sp. (4.0 μg mL−1) and phycocyanin in Leptolyngbya sp. (60 μg mL−1). Higher total proteins were found in the genus Geitlerinema (75% DW), carbohydrates in Microcystis navacekii (30% DW) and lipids in Phormidium sp. (15% DW). Furthermore, Aphanocapsa holsatica showed the highest antioxidant activity (65%) and Sphaerocavum brasiliense, Microcystis aeruginosa, Nostoc sp. (CCIBt3249) and A. holsatica higher levels of PHA (~ 2% DW). This study reports on the biochemical composition of cyanobacteria that can impact the biotechnology of their production, highlighting potential strains with high productivity of specific biomolecules.
|
|
BORDIN, EDUARDA ROBERTA;
YAMAMOTO, FLAVIA YOSHIE;
MANNES, YORRANNYS;
MUNHOZ, RENAN CÉSAR;
MUELBERT, JUAN RAMON ESQUIVEL;
DE FREITAS, ADRIANE MARTINS;
Cestari, M.M.;
Ramsdorf, W.A.
Palavra-chave:
Toxicidade;
Genotoxicidade;
ecogenotoxicidade
Áreas do conhecimento:
Ciências Biológicas; Genética; Genética Animal; Mutagênese Ambiental;
Ciências Biológicas; Genética; Genotoxicidade em Peixes
resumo ...
|
|
Bruna Salemme;
Ana Maria Raymundi;
Jeferson M. B. Sohn;
Cristina Aparecida Jark Stern
Palavra-chave:
anandamida;
ansiedade;
fêmeas;
estradiol;
2-AG
Áreas do conhecimento:
Ciências Biológicas; Farmacologia; Neuropsicofarmacologia
resumo ...
|
|
CALONGA-SOLÍS, VERÓNICA;
BUSCH, HAUKE;
FÄHNRICH, ANKE;
Augusto, Danillo G.;
OLBRICH, MICHAEL;
OTT, FABIAN;
ADELMAN CIPOLLA, GABRIEL;
Danielle Malheiros Ferreira;
KÜNSTNER, AXEL;
FARIAS, TICIANA D.J.;
CAMARGO, CAROLINA M.;
Maria Luiza Petzl-Erler
Palavra-chave:
pemphigus foliaceus;
immunoglobulin repertoire;
Fogo selvagem;
Autoimmunity;
skin disease;
B cells
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Imunologia; Imunogenética
resumo ...
|
|
KAZIUK, FERNANDO DIEGO;
FURLANETTO, ANA LUIZA DORIGAN DE MATOS;
DOS SANTOS, ANDRÉ LUIS WENDT;
FLOH, ENY IOCHEVET SENEGAL;
Donatti, Lucélia;
MERLIN ROCHA, MARIA ELIANE;
FORTES, FABIANE;
MARTINEZ, GLAUCIA REGINA;
CADENA, SILVIA MARIA SUTER CORREIA
Palavra-chave:
Araucaria;
Heat stress;
bioenergetics
Áreas do conhecimento:
Ciências Biológicas; Bioquímica; Bioquímica
resumo ...
|
|
OLIVEIRA, LUANA CAROLINE;
Maria Luiza Petzl-Erler;
Boldt, Angelica Beate Winter;
DORNELLES, AMANDA COELHO;
NISIHARA, RENATO MITSUNORI;
BRUGINSKI, ESTEVAN RAFAEL DUTRA;
SANTOS, PRISCILA IANZEN DOS;
CIPOLLA, GABRIEL ADELMAN;
BOSCHMANN, STEFANIE EPP;
Messias-Reason, Iara José de;
CAMPOS, FRANCINETE RAMOS
Palavra-chave:
Celiac disease;
Mennonites;
Prevalence;
metabolism
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica
resumo ...
|
|
OLIVEIRA, LUANA CAROLINE;
Petzl-Erler, Maria Luiza;
Angelica Beate Winter Boldt;
DORNELLES, AMANDA COELHO;
NISIHARA, RENATO MITSUNORI;
BRUGINSKI, ESTEVAN RAFAEL DUTRA;
SANTOS, PRISCILA IANZEN DOS;
CIPOLLA, GABRIEL ADELMAN;
BOSCHMANN, STEFANIE EPP;
Messias-Reason, Iara José de;
CAMPOS, FRANCINETE RAMOS
Palavra-chave:
Doença Celíaca;
HLA-DQ;
Efeito fundador;
menonita;
transglutaminase;
anti-endomísio
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética;
Ciências Biológicas; Genética; Genética Humana e Médica; Genética de Populacoes
resumo ...
Celiac disease (CD), despite its high morbidity, is an often-underdiagnosed autoimmune enteropathy. Using a modified version of the Brazilian questionnaire of the 2013 National Health Survey, we interviewed 604 Mennonites of Frisian/Flemish origin that have been isolated for 25 generations. A subgroup of 576 participants were screened for IgA autoantibodies in serum, and 391 participants were screened for HLA-DQ2.5/DQ8 subtypes. CD seroprevalence was 1:29 (3.48%, 95% CI = 2.16–5.27%) and biopsy-confirmed CD was 1:75 (1.32%, 95% CI = 0.57–2.59%), which is superior to the highest reported global prevalence (1:100). Half (10/21) of the patients did not suspect the disease. HLA-DQ2.5/DQ8 increased CD susceptibility (OR = 12.13 [95% CI = 1.56–94.20], p = 0.003). The HLA-DQ2.5 carrier frequency was higher in Mennonites than in Brazilians (p = 7 × 10−6). HLA-DQ8 but not HLA-DQ2.5 carrier frequency differed among settlements (p = 0.007) and was higher than in Belgians, a Mennonite ancestral population (p = 1.8 × 10−6), and higher than in Euro-Brazilians (p = 6.5 × 10−6). The glutathione pathway, which prevents reactive oxygen species-causing bowel damage, was altered within the metabolic profiles of untreated CD patients. Those with lower serological positivity clustered with controls presenting close relatives with CD or rheumatoid arthritis. In conclusion, Mennonites have a high CD prevalence with a strong genetic component and altered glutathione metabolism that calls for urgent action to alleviate the burden of comorbidities due to late diagnosis.
|
|
LAMAS, CARLOS JOSÉ EINICKER;
BELLODI, CAROLINA FERRAZ;
Freddy Bravo;
CALHAU, JULIA;
CAPELLARI, RENATO SOARES;
CARMO-NETO, ANTONIO MARCELINO DO;
CEGOLIN, BIANCA MELO;
Marcia Souto COURI;
Cláudio J B Carvalho;
DIOS, RODRIGO DE VILHENA PEREZ;
FALCON, AIDA VANESSA GOMEZ;
FACHIN, DIEGO AGUILAR;
FUSARI, LIVIA MARIA;
FALASCHI, RAFAELA LOPES;
ALCANTARA, DANIEL MÁXIMO CORREA DE;
Rosaly Ale-Rocha;
Dalton de Souza Amorim;
ARAÚJO, MAÍRA XAVIER;
ASCENDINO, SHARLENE;
BALDASSIO, LETÍCIA
Palavra-chave:
biodiversity;
endemism;
inventory;
Neotropical region
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Biogeografia
resumo ...
ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the...
|
|
Gerard Piñol-Ripoll1;
Marcelo M. S. Lima;
Shi-Bin Li;
Adriano Dias Targa
Palavra-chave:
sleep;
Circadian rhtyms;
Neurodegenerative diseasaes;
Alzheiemer?s disease;
Parknson's disease
Áreas do conhecimento:
Ciências Biológicas; Fisiologia; Neurofisiologia
resumo ...
|
