Publicações - ciências biológicas
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TINCANI, F.H.;
SILVA, C.P.;
C A Oliveira Ribeiro;
SILVA DE ASSIS, H.C.;
CAMPOS, S.X.;
Ramsdorf, W.A.;
Cestari, M.M.;
Gustavo Souza Santos;
Ana Carolina Barni Azevedo;
Antônio Ernesto Meister Luz Marques;
Letícia da Silva Pereira;
CASTELLANO, G.C.;
DA SILVA, T.A.;
GALVAN, G.L.;
Fábio Gaio Chimentão
Palavra-chave:
ensaio cometa;
Enzimas;
Estresse Oxidativo;
Lambari;
Peixes
Áreas do conhecimento:
Ciências Biológicas; Genética; Genética Animal; Mutagênese Ambiental;
Ciências Biológicas; Genética; Genotoxicidade em Peixes;
Ciências Biológicas; Ecologia; Ecologia Aplicada; Ecotoxicologia
resumo ...
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DORIGAN DE MATOS FURLANETTO, A. L.;
VALENTE, CAROLINE;
MARTINEZ, GLAUCIA REGINA;
ROCHA, MARIA ELIANE MERLIN;
Maurer, Juliana Bello Baron;
Silvia Maria Suter C Cadena
Palavra-chave:
Araucaria angustifolia;
oxidative stress
Áreas do conhecimento:
Ciências Biológicas; Metabolismo e Bioenergética; Metabolismo energético em plantas;
Ciências Biológicas; Bioquímica; Radicais Livres e Estresse Oxidativo; Radicais Livres e Estresse Oxidativo
resumo ...
Araucaria angustifolia (Bert.) O. Kuntze is a species critically endangered of extinction and its development and propagation is strongly affected by abiotic stress. We have previously shown the ac...
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SANTOS, EMILI B;
FAVRETTO, MARIO A;
Mário Antonio NavarroSilva
Palavra-chave:
Diptera;
Culicidae;
Anopheles cruzii;
Bioecologia de Culicidae;
Culex abonnenci
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Comportamento Animal
resumo ...
Considering the importance of Culicidae species to public health, this study aimed to update and provide better understanding of the mosquito fauna in an Atlantic Forest preservation area in Paranagu...
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Daniel Pacheco Bruschi;
SOUSA, DEBORAH YASMIM;
Amanda Araújo Soares;
CARVALHO, KLÉLIA APARECIDA DE;
Busin, Carmen Sílvia;
FICANHA, NATÁLIA CRISTINE;
LIMA, ALBERTINA PIMENTEL;
Andrade, Gilda Vasconcellos;
Shirlei Maria Recco-Pimentel
Palavra-chave:
citogenética;
Rhinela
resumo ...
Abstract The genus Rhinella is one of the most diverse groups of bufonid toads, currently...
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BACH, FERNANDO SWIECH;
Fabiano Montiani Ferreira;
VILLANOVA, JOSÉ ADEMAR;
REBELATTO, CARMEN LUCIA KUNIYOSHI;
FRACARO, LETICIA;
SENEGAGLIA, ALEXANDRA CRISTINA;
FRAGOSO, FELIPE YUKIO ISHIKAWA;
Daga, Debora Regina;
BROFMAN, PAULO ROBERTO SLUD;
PIMPÃO, CLAUDIA TURRA;
ENGRACIA FILHO, JAIR RODINI
Palavra-chave:
neurologia;
stem cells;
laminectomy
Áreas do conhecimento:
CIENCIAS_AGRARIAS; Clínica e Cirurgia Animal; Neurologia Veterinária;
CIENCIAS_AGRARIAS; Medicina Veterinária; Patologia Animal;
Ciências Biológicas; Morfologia; Anatomia; Anatomia Animal
resumo ...
Paraparesis and paraplegia are common conditions in dogs, most often caused by a disc herniation in the thoracolumbar spinal segments (T3-L3), which is a neurological emergency. Surgical decompression should be performed as soon as possible when spinal compression is revealed by myelography, computed tomography, or magnetic resonance imaging. Mesenchymal stem-cell therapy is a promising adjunct treatment for spinal cord injury. This study sought to compare the effects of surgical decompression alone and combined with an allogeneic transplantation of canine adipose tissue-derived mesenchymal stem cells (cAd-MSCs) in the treatment of dogs with acute paraplegia. Twenty-two adult dogs of different breeds with acute paraplegia resulting from a Hansen type I disc herniation in the thoracolumbar region (T3-L3) were evaluated using computed tomography. All dogs had grade IV or V lesions and underwent surgery within 7 days after symptom onset. They were randomly assigned into two groups, 11 dogs in each. The dogs in Group I underwent hemilaminectomy, and those in Group II underwent hemilaminectomy and cAd-MSC epidural transplantation. In both groups, all dogs with grade IV lesions recovered locomotion. The median locomotion recovery period was 7 days for Group II and 21 days for Group I, and this difference was statistically significant (p p
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Luana Caroline de Oliveira;
Hauke Busch;
Enno Schmidt;
Maria Luiza Petzl-Erler;
Angelica Beate Winter Boldt;
Gabriela Canalli Kretzschmar;
Andressa Cristina Matoso;
Carolina M. Camargo;
Mariana Basso Spadoni;
Renato Mitsunori Nisihara;
Ticiana D. J. Farias;
Andre Franke;
Michael Witting
Palavra-chave:
CR1;
sCR1;
complemento;
pênfigo foliáceo;
receptor 1 do complemento;
haplótipo
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética
resumo ...
Pemphigus foliaceus is an autoimmune disease that is sporadic around the world but endemic in Brazil, where it is known as fogo selvagem (FS). Characterized by autoantibodies against the desmosomal cadherin desmoglein 1, FS causes painful erosions, and crusts that may be widespread. The recognition of antigens, including exposed sugar moieties, activates the complement system. Complement receptor 1 (CR1, CD35), which is responsible for the Knops blood group on erythrocytes (York and McCoy antigens), is also expressed by antigen-presenting cells. This regulates the complement system by removing opsonized antigens, blocking the final steps of the complement cascade. Membrane-bound CR1 also fosters antigen presentation to B cells, whereas soluble CR1 has anti-inflammatory properties. CR1 gene polymorphisms have been associated with susceptibility to complex diseases. In order to investigate the association of CR1 polymorphisms with FS susceptibility, we developed a multiplex sequence-specific assay to haplotype eleven polymorphisms in up to 367 FS patients and 242 controls from an endemic area and 289 from a non-endemic area. We also measured soluble CR1 (sCR1) in the serum of 53 FS patients and 27 controls and mRNA levels in the peripheral blood mononuclear cells of 63 genotyped controls. The haplotypes CR1*3B2B (with the York antigen–encoded by p.1408Met) and CR1*3A2A (with p.1208Arg) were associated with protection against FS (OR = 0.57, P = 0.027, and OR = 0.46, P = 0.014...
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CRUZ, MAIARA A.;
PERONTI, ANA LÚCIA B. G.;
MARTINELLI, NILZA M.;
COSTA, VALMIR A.;
IGNÁCIO, GABRIELA P.;
Almeida, LM.
Palavra-chave:
Ecological interactions;
Parasitoids;
predators
Áreas do conhecimento:
Ciências Biológicas; Controle Biológico;
Ciências Biológicas; Zoologia; Entomologia
resumo ...
(en)
A survey of the natural enemies of Aclerda takahashii (Kuwana, 1932) (Hemiptera: Aclerdidae) and Saccharicoccus sacchari (Cockerell, 1895) (Hemiptera: Pseudococcidae) was carried out in the state of São Paulo, Brazil. A total of ten associations were recorded, six parasitoid-host and four predator-prey, which three are new: parasitoids of the genus Eurytoma (Hymenoptera: Eurytomidae) and Hambletonia (Hymenoptera: Encyrtidae) associated with A. takahashii and S. sacchari, respectively; and the predator of the genus Diadiplosis (Diptera: Cecidomyiidae) with a S. sacchari. Anagyrus saccharicola Timberlake, 1932 and Mariola flava Noyes, 1980 (Hymenoptera: Encyrtidae) are reported for the first time in Brazil.
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MARTINS BASSACO, MARCOS VINÍCIUS;
Antonio Carlos Nogueira
Palavra-chave:
Autoecologia vegetal;
Floresta Ombrófila Mista Aluvial;
Restauração florestal;
branquilho-leitero
Áreas do conhecimento:
CIENCIAS_AGRARIAS; Sementes Florestais;
Ciências Biológicas; Ecologia; Ecologia Aplicada
resumo ...
(en)
In view of the growing need for biological knowledge of native species for use in riparian forest restoration projects, the aim of this work was the phenological characterization of Sebastiania brasiliensis, a shrubby tree species that occurs in the alluvial mixed ombrophilous forest. Accordingly, ten trees were monitored in the municipality of Araucária, PR, Brazil, observing the reproductive and vegetative phenological events. The reproductive and vegetative phenophases showed seasonality. The reproductive phases began in early summer with the appearance of the first floral buds and ended with the ripe fruit in early spring, while the vegetative phases began in the winter, occurring during leaf fall and with return of the leaves in spring. Although the phenophases exhibited the described seasonality, they did not show a correlation with climatic variables (temperature, relative humidity and precipitation) during the period evaluated. Therefore, we can conclude that reproductive phenophases have a higher seasonality than vegetative ones, and that the species has well-defined phenological patterns, but further studies of longer duration are indicated.
(pt)
Com a necessidade crescente do conhecimento biológico das espécies nativas para utilização em projetos de restauração de matas ciliares, este trabalho teve como objetivo a caracterização fenológica de Sebastiania brasiliensis, espécie arbórea arbustiva que ocorre na Floresta Ombrófila Mista Aluvial. Para isso, foi feito o acompanhamento de dez árvores no município de Araucária – PR, observando os eventos fenológicos reprodutivos e vegetativos. As fenofases reprodutivas e vegetativas apresentaram sazonalidade, sendo que as fases reprodutivas iniciaram no início do verão com o aparecimento dos primeiros botões florais e finalizaram com o fruto maduro no início da primavera, enquanto as fenofases vegetativas iniciaram no inverno, ocorrendo a queda das ocorrendo a queda das folhas, que retornaram na primavera. Embora as fenofases tenham apresentado a sazonalidade descrita, ela não apresentou correlação com as variáveis climáticas (temperatura, umidade relativa e precipitação) durante o período avaliado. Dessa forma pode-se concluir que as fenofases reprodutivas apresentam maior sazonalidade que as vegetativas, e que a espécie apresenta padrões fenológicos bem definidos, porém estudos com maior tempo de duração são indicados.
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BUMILLER-BINI, VALÉRIA;
CIPOLLA, GABRIEL ADELMAN;
SPADONI, MARIANA BASSO;
Augusto, Danillo G.;
Maria Luiza Petzl-Erler;
BELTRAME, MARCIA HOLSBACH;
Boldt, Angelica Beate Winter
Palavra-chave:
COMPLEMENT SYSTEM;
Pemphigus;
Fogo selvagem;
Genetic polymorphism;
regulated cell death;
RCD
resumo ...
Pemphigus foliaceus (PF) is an autoimmune blistering skin disease that occurs sporadically across the globe and is endemic in Brazil. Keratinocyte adhesion loss (acantholysis) is associated with high levels of anti-desmoglein 1 IgG autoantibodies, but the role of cell death is poorly understood in PF. Current evidence disqualifies apoptosis as the major cell death mechanism and no other process has yet been investigated. To approach the role of variation in genes responsible for cell death pathways in pemphigus susceptibility, we systematically investigated the frequencies of 1,167 polymorphisms from genes encoding products of all 12 well-established cell death cascades (intrinsic and extrinsic apoptosis, necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic, NETotic, lysosome-dependent, autophagy-dependent, and immunogenic). By multivariate logistic regression, we compared allelic and genotypic frequencies of 227 PF patients and 194 controls obtained by microarray hybridization. We found 10 variants associated with PF (p TNF, TRAF2, CD36, and PAK2), immunogenic cell death (EIF2AK3, CD47, and SIRPA), necroptosis (TNF and TRAF2), necrosis (RAPGEF3), parthanatos (HK1), and pyroptosis (PRKN). Five polymorphisms were associated with susceptibility: TNF rs1800630*A (OR = 1.9, p = 0.0003), CD36 rs4112274*T (OR = 2.14, p = 0.0015), CD47 rs12695175*G (OR = 1.77, p = 0.0043), SIRPA rs6075340*A/A (OR = 2.75, p = 0.0009), and HK1 rs7072268*T (OR = 1.48, p = 0.0045). Ot...
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BINI, VALÉRIA BUMILLER;
Gabriel Adelman Cipolla;
Mariana Basso Spadoni;
danillo gardenal augusto;
Maria Luiza PetzlErler;
Márcia Holsbach Beltrame;
Angelica Beate Winter Boldt
Palavra-chave:
pemphigus foliaceus;
via imunogênica de morte celular;
Apoptose;
polimorfismo;
inflamassoma;
necroptose
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética
resumo ...
Pemphigus foliaceus (PF) is an autoimmune blistering skin disease that occurs sporadically across the globe and is endemic in Brazil. Keratinocyte adhesion loss (acantholysis) is associated with high levels of anti-desmoglein 1 IgG autoantibodies, but the role of cell death is poorly understood in PF. Current evidence disqualifies apoptosis as the major cell death mechanism and no other process has yet been investigated. To approach the role of variation in genes responsible for cell death pathways in pemphigus susceptibility, we systematically investigated the frequencies of 1,167 polymorphisms from genes encoding products of all 12 well-established cell death cascades (intrinsic and extrinsic apoptosis, necrosis, necroptosis, ferroptosis, pyroptosis, parthanatos, entotic, NETotic, lysosome-dependent, autophagy-dependent, and immunogenic). By multivariate logistic regression, we compared allelic and genotypic frequencies of 227 PF patients and 194 controls obtained by microarray hybridization. We found 10 variants associated with PF (p TNF, TRAF2, CD36, and PAK2), immunogenic cell death (EIF2AK3, CD47, and SIRPA), necroptosis (TNF and TRAF2), necrosis (RAPGEF3), parthanatos (HK1), and pyroptosis (PRKN). Five polymorphisms were associated with susceptibility: TNF rs1800630*A (OR = 1.9, p = 0.0003), CD36 rs4112274*T (OR = 2.14, p = 0.0015), CD47 rs12695175*G (OR = 1.77, p = 0.0043), SIRPA rs6075340*A/A (OR = 2.75, p = 0.0009), and HK1 rs7072268*T (OR = 1.48, p = 0.0045). Ot...
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