Publicações - ciências biológicas
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Bruna Salemme;
Ana Maria Raymundi;
Jeferson M. B. Sohn;
Cristina Aparecida Jark Stern
Palavra-chave:
anandamida;
ansiedade;
fêmeas;
estradiol;
2-AG
Áreas do conhecimento:
Ciências Biológicas; Farmacologia; Neuropsicofarmacologia
resumo ...
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OLIVEIRA, LUANA CAROLINE;
Petzl-Erler, Maria Luiza;
Angelica Beate Winter Boldt;
DORNELLES, AMANDA COELHO;
NISIHARA, RENATO MITSUNORI;
BRUGINSKI, ESTEVAN RAFAEL DUTRA;
SANTOS, PRISCILA IANZEN DOS;
CIPOLLA, GABRIEL ADELMAN;
BOSCHMANN, STEFANIE EPP;
Messias-Reason, Iara José de;
CAMPOS, FRANCINETE RAMOS
Palavra-chave:
Doença Celíaca;
HLA-DQ;
Efeito fundador;
menonita;
transglutaminase;
anti-endomísio
Áreas do conhecimento:
Ciências Biológicas; Genética Humana e Médica;
Ciências Biológicas; Genética; Genética Humana e Médica; Imunogenética;
Ciências Biológicas; Genética; Genética Humana e Médica; Genética de Populacoes
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Celiac disease (CD), despite its high morbidity, is an often-underdiagnosed autoimmune enteropathy. Using a modified version of the Brazilian questionnaire of the 2013 National Health Survey, we interviewed 604 Mennonites of Frisian/Flemish origin that have been isolated for 25 generations. A subgroup of 576 participants were screened for IgA autoantibodies in serum, and 391 participants were screened for HLA-DQ2.5/DQ8 subtypes. CD seroprevalence was 1:29 (3.48%, 95% CI = 2.16–5.27%) and biopsy-confirmed CD was 1:75 (1.32%, 95% CI = 0.57–2.59%), which is superior to the highest reported global prevalence (1:100). Half (10/21) of the patients did not suspect the disease. HLA-DQ2.5/DQ8 increased CD susceptibility (OR = 12.13 [95% CI = 1.56–94.20], p = 0.003). The HLA-DQ2.5 carrier frequency was higher in Mennonites than in Brazilians (p = 7 × 10−6). HLA-DQ8 but not HLA-DQ2.5 carrier frequency differed among settlements (p = 0.007) and was higher than in Belgians, a Mennonite ancestral population (p = 1.8 × 10−6), and higher than in Euro-Brazilians (p = 6.5 × 10−6). The glutathione pathway, which prevents reactive oxygen species-causing bowel damage, was altered within the metabolic profiles of untreated CD patients. Those with lower serological positivity clustered with controls presenting close relatives with CD or rheumatoid arthritis. In conclusion, Mennonites have a high CD prevalence with a strong genetic component and altered glutathione metabolism that calls for urgent action to alleviate the burden of comorbidities due to late diagnosis.
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LAMAS, CARLOS JOSÉ EINICKER;
BELLODI, CAROLINA FERRAZ;
Freddy Bravo;
CALHAU, JULIA;
CAPELLARI, RENATO SOARES;
CARMO-NETO, ANTONIO MARCELINO DO;
CEGOLIN, BIANCA MELO;
Marcia Souto COURI;
Cláudio J B Carvalho;
DIOS, RODRIGO DE VILHENA PEREZ;
FALCON, AIDA VANESSA GOMEZ;
FACHIN, DIEGO AGUILAR;
FUSARI, LIVIA MARIA;
FALASCHI, RAFAELA LOPES;
ALCANTARA, DANIEL MÁXIMO CORREA DE;
Rosaly Ale-Rocha;
Dalton de Souza Amorim;
ARAÚJO, MAÍRA XAVIER;
ASCENDINO, SHARLENE;
BALDASSIO, LETÍCIA
Palavra-chave:
biodiversity;
endemism;
inventory;
Neotropical region
Áreas do conhecimento:
Ciências Biológicas; Bioquímica dos Microorganismos; Enzimologia;
Ciências Biológicas; Zoologia; Biogeografia
resumo ...
ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the...
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BARRETO, LUIZA SANTOS;
SOUZA, TUGSTÊNIO LIMA DE;
MORAIS, TOBIAS PEREIRA DE;
C A Oliveira Ribeiro
Palavra-chave:
ecotoxicologia;
Estagio Inicial de desenvolvimento;
glifosato;
Reservatórios;
Rio Iguaçu
Áreas do conhecimento:
Ciências Biológicas; Ecologia Aplicada; Ecotoxicologia;
Ciências Biológicas; Zoologia; Zoologia Aplicada; Conservação das Espécies Animais
resumo ...
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FONSECA, RENATO ITAMAR DUARTE;
MENEZES, LEOCILEY ROCHA ALENCAR;
SANTANA-FILHO, ARQUIMEDES PAIXÃO;
SCHIEFER, ELBERTH MANFRON;
PECOITS-FILHO, Roberto;
Andréa Emília Marques Stinghen;
SASSAKI, GUILHERME LANZI
Palavra-chave:
chronic kidney disease;
Metabolomics
Áreas do conhecimento:
Ciências da Saúde; Medicina; Clínica Médica; Nefrologia;
Ciências Biológicas; Bioquímica; Bioquímica
resumo ...
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GOMES, LUCAS ROBERTO PEREIRA;
Cláudio J B Carvalho
Palavra-chave:
Ancestral distribution;
biodiversity;
morphological characters;
Neotropical
Áreas do conhecimento:
Ciências Biológicas; Zoologia; Taxonomia dos Grupos Recentes
resumo ...
Abstract Coenosopsia Malloch has eight known species distributed from southern North America to south-eastern South America. The species of the genus are morphologically very homogeneous, and major differences remain in male terminalia. Remarkably, two of the main diagnostic characteristics of Anthomyiidae are absent in this genus: the setulae on the ventral surface of the scutellum and vein A1 reaching the wing margin. Some studies have attempted to propose biogeographical narratives, primarily for the Neotropical distribution of the genus. Herein, we describe three new species of Coenosopsia from north-eastern Brazil (Coenosopsia limeirai sp. nov.), southern Brazil (Coenosopsia ribeiroi sp. nov.), and central Mexico (Coenosopsia azteca sp. nov.) and present an identification key. In addition, we present an updated phylogenetic analysis based on morphological evidence, which recovered Coenosopsia as monophyletic based on five synapomorphies and four homoplasies. We also presented the first biogeographical hypothesis of Coenosopsia based on biogeographic methods (ancestral reconstruction character and S-DIVA analyses), which indicated a Mesoamerican origin of the genus.
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Cynton Lourenço Corrêa;
Carlos Augusto Borges de Andrade Gomes;
Andressa de Abreu Mello;
Nathany da Silva Nogueira;
Taiane Barreto Medeiros;
Cintia Monteiro de Barros;
Silvana Allodi
Palavra-chave:
Parkinson's disease;
Chemicals;
invertebrates
Áreas do conhecimento:
Ciências Biológicas; Fisiologia; Neurociências
resumo ...
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A L FILADELPHO;
A L FILADELPHO;
A L FILADELPHO;
A L FILADELPHO;
A L FILADELPHO
Palavra-chave:
Criopreservação;
ensino de anatomia;
Sistema Digestório;
ovinos
Áreas do conhecimento:
CIENCIAS_AGRARIAS; Tecnologia de Alimentos;
Ciências Biológicas; Morfologia; Anatomia; Anatomia Animal
resumo ...
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Carolina Zaghi Cavalcante;
Pedro Vicente Michelotto júnior;
Luiz Guilherme Achnar Capriglione;
Andressa Thais Roncoski;
Anita Nishiyama
Palavra-chave:
cães;
obesos;
inflamação;
cortisol
Áreas do conhecimento:
CIENCIAS_AGRARIAS; Tecnologia de Alimentos;
Ciências Biológicas; Fisiologia; Fisiologia Geral
resumo ...
In obese dogs, oxidative stress is associated with inflammatory processes and systemic endocrine imbalances. Monitoring oxidative status is an early and valuable means of obesity control as it is a marker of weight loss, which leads to a reduction in oxidative status or injury potential. The objecti …
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Marcos José Oliveira;
Francisca Helena Aguiar-Silva;
Wanderlei de Moraes;
Tânia Margarete Sanaiotti;
Aureo Banhos;
Nei Moreira
Palavra-chave:
aves de rapina;
reprodução em cativeiro;
espécies ameaçadas;
Harpia harpyja
Áreas do conhecimento:
Ciências Biológicas; Zoologia; Zoologia Aplicada; Conservação das Espécies Animais;
Ciências Biológicas; Zoologia; Zoologia Aplicada; Conservação das Espécies Animais;
Ciências Biológicas; Ecologia; Ecologia Aplicada; Conservação e Manejo de Espécies Ameaçadas
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A main priority in conservation is the protection of species in their natural habitat. However, ex situ management of threatened species is a recognised strategy of conservation. Harpy Eagles (Harpia harpyja) are removed from the wild due to illegal capture, nest tree destruction, or other conflict sources. This study presents a review of the current ex situ Harpy Eagle populations in Brazil and worldwide, including information on the origin, sex, and year of entrance or year of birth under human care. Worldwide, until 2020 there were 205 Harpy Eagles in 77 different facilities in 16 countries, with 40 institutions in Brazil and 37 in other countries. The largest ex situ Harpy Eagle population is maintained in Brazil, with 139 individuals (75 females and 64 males) in 40 institutions. Of these institutions, there were 24 zoos, seven conservation breeding centres, six commercial breeders, two wildlife shelters, and one wildlife sorting centre. In Brazil, 62% (n = 86) of the individuals were hatched in the wild and 38% (n = 53) were bred in captivity under human care; for the wild individuals, only 73% (n = 64) have a known state of origin, with the majority from Pará state. This investigation provided relevant information to establish an ex situ demographic database. These individuals may potentially constitute a genetically and demographically viable safety population for future conservation strategies, as well as a source for research and education applied to Harpy Eagle integrated conservation.
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